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Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure

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Title: Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure
Authors: Terui, Hiroya Browse this author
Konno, Satoshi Browse this author →KAKEN DB
Kaga, Kichizo Browse this author →KAKEN DB
Matsuno, Yoshihiro Browse this author
Hatanaka, Kanako C. Browse this author
Kanno, Hiromi Browse this author
Moriyama, Hiroshi Browse this author
Uo, Motohiro Browse this author →KAKEN DB
Nishimura, Masaharu Browse this author →KAKEN DB
Keywords: Hard metal lung disease
Pulmonary function
Dust exposure
Avoidance
BALF
Issue Date: 5-Aug-2015
Publisher: BioMed Central
Journal Title: Journal of occupational medicine and toxicology
Volume: 10
Start Page: 29
Publisher DOI: 10.1186/s12995-015-0070-9
Abstract: We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolution computed tomography were modest. The increased lymphocytes and decreased CD4/CD8 ratio in BALF observed at initial diagnosis normalized after the avoidance of dust exposure in one case. To the best of our knowledge, this is the first report demonstrating continual follow-up of pulmonary function and radiographic findings, and a comparison of BALF findings before and after avoidance of hard metal dust exposure.
Rights: http://creativecommons.org/licenses/by/4.0
Type: article
URI: http://hdl.handle.net/2115/59819
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 今野 哲

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