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Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure
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| Title: | Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure |
| Authors: | Terui, Hiroya Browse this author | | Konno, Satoshi Browse this author →KAKEN DB | | Kaga, Kichizo Browse this author →KAKEN DB | | Matsuno, Yoshihiro Browse this author | | Hatanaka, Kanako C. Browse this author | | Kanno, Hiromi Browse this author | | Moriyama, Hiroshi Browse this author | | Uo, Motohiro Browse this author →KAKEN DB | | Nishimura, Masaharu Browse this author →KAKEN DB |
| Keywords: | Hard metal lung disease | | Pulmonary function | | Dust exposure | | Avoidance | | BALF |
| Issue Date: | 5-Aug-2015 |
| Publisher: | BioMed Central |
| Journal Title: | Journal of occupational medicine and toxicology |
| Volume: | 10 |
| Start Page: | 29 |
| Publisher DOI: | 10.1186/s12995-015-0070-9 |
| Abstract: | We present herein two cases of hard metal lung disease (HMLD) with distinct pathological findings. Both cases showed gradual improvements in pulmonary function over a period of a few years (Case 1: 30 months; Case 2: 12 months) after the avoidance of dust exposure, while improvements on high-resolution computed tomography were modest. The increased lymphocytes and decreased CD4/CD8 ratio in BALF observed at initial diagnosis normalized after the avoidance of dust exposure in one case. To the best of our knowledge, this is the first report demonstrating continual follow-up of pulmonary function and radiographic findings, and a comparison of BALF findings before and after avoidance of hard metal dust exposure. |
| Rights: | http://creativecommons.org/licenses/by/4.0 |
| Type: | article |
| URI: | http://hdl.handle.net/2115/59819 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 今野 哲
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