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Volume 63 Number 3 >

Molecular characterization of Mycobacterium orygis isolates from wild animals of Nepal

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.63.3.151

Title: Molecular characterization of Mycobacterium orygis isolates from wild animals of Nepal
Authors: Thapa, Jeewan Browse this author
Nakajima, Chie Browse this author →KAKEN DB
Maharjan, Bhagwan Browse this author
Poudel, Ajay Browse this author
Suzuki, Yasuhiko Browse this author →KAKEN DB
Keywords: Mycobacterial interspersed repetitive units-variable number of tandem repeats
Mycobacterium orygis
Spoligotyping
Wild animals
Issue Date: Aug-2015
Publisher: Graduate School of Veterinary Medicine, Hokkaido University
Journal Title: Japanese Journal of Veterinary Research
Volume: 63
Issue: 3
Start Page: 151
End Page: 158
Abstract: Mycobacterium orygis, a new member of the Mycobacterium tuberculosis complex, was isolated from a captive spotted deer (Axis axis) and a blue bull (Boselaphus tragocamelus) in Nepal. Analyses by spoligotyping, mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) typing, region of difference and single nucleotide polymorphism of genes gyrB, mmpL6, TbD1, PPE55 and Rv2042c confirmed the isolates as M. orygis. Moreover, analyses by spoligotyping (SIT587) as well as MIRU-VNTR showed that the isolates shared a similar pattern with many reported isolates. From previous and the present studies, it can be inferred that South Asia is one of the endemic regions for M. orygis. Further investigation including a larger sample size and different host interaction will help to understand the ecology and epidemiology of M. orygis in Nepal.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/59877
Appears in Collections:Japanese Journal of Veterinary Research > Volume 63 Number 3

Submitter: 獣医学部図書室

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