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Model for calcium-mediated reduction of structural fluctuations in epidermis

PhysRevE.92.022709.pdf480.96 kBPDF見る/開く

タイトル: Model for calcium-mediated reduction of structural fluctuations in epidermis
著者: Kobayashi, Yasuaki 著作を一覧する
Kitahata, Hiroyuki 著作を一覧する
Nagayama, Masaharu 著作を一覧する
発行日: 2015年 8月13日
出版者: American Physical Society
誌名: Physical review E
巻: 92
号: 2
開始ページ: 022709-1
終了ページ: 022709-7
出版社 DOI: 10.1103/PhysRevE.92.022709
抄録: We propose a reaction-advection-diffusion model of epidermis consisting of two variables, the degree of differentiation and the calcium ion concentration, where calcium ions enhance differentiation. By analytically and numerically investigating this system, we show that a calcium localization layer formed beneath the stratum corneum helps reduce spatiotemporal fluctuations of the structure of the stratum corneum. In particular, spatially or temporally small-scale fluctuations in the lower structure are suppressed and do not affect the upper structure, due to acceleration of differentiation by calcium ions. Analytical expressions for the reduction rate of fluctuation amplitudes are shown.
Rights: ©2015 American Physical Society
資料タイプ: article
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 小林 康明


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