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Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy

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Title: Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy
Authors: Onodera, Jun Browse this author
Kondo, Eiji Browse this author →KAKEN DB
Omizu, Nobuyuki Browse this author
Ueda, Daisuke Browse this author
Yagi, Tomonori Browse this author
Yasuda, Kazunori Browse this author →KAKEN DB
Keywords: Open-wedge high tibial osteotomy
Beta-tricalcium phosphate
Hydroxyapatite
Wedge-shaped spacer
Knee osteoarthritis
Issue Date: Nov-2014
Publisher: Springer
Journal Title: Knee surgery sports traumatology arthroscopy
Volume: 22
Issue: 11
Start Page: 2763
End Page: 2770
Publisher DOI: 10.1007/s00167-013-2681-y
PMID: 24045917
Abstract: The purpose of this study was to clinically and radiologically compare the utility, osteoconductivity, and absorbability of hydroxyapatite (HAp) and beta-tricalcium phosphate (TCP) spacers in medial open-wedge high tibial osteotomy (HTO). Thirty-eight patients underwent medial open-wedge HTO with a locking plate. In the first 19 knees, a HAp spacer was implanted in the opening space (HAp group). In the remaining 19 knees, a TCP spacer was implanted in the same manner (TCP group). All patients underwent clinical and radiological examinations before surgery and at 18 months after surgery. Concerning the background factors, there were no statistical differences between the two groups. Post-operatively, the knee score significantly improved in each group. Concerning the post-operative knee alignment and clinical outcome, there was no statistical difference in each parameter between the two groups. Regarding the osteoconductivity, the modified van Hemert's score of the TCP group was significantly higher (p = 0.0009) than that of the HAp group in the most medial osteotomy zone. The absorption rate was significantly greater in the TCP group than in the HAp group (p = 0.00039). The present study demonstrated that a TCP spacer was significantly superior to a HAp spacer concerning osteoconductivity and absorbability at 18 months after medial open-wedge HTO. Retrospective comparative study, Level III.
Rights: The final publication is available at link.springer.com
Type: article (author version)
URI: http://hdl.handle.net/2115/60250
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 小野寺 純

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