Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation
This item is licensed under:Creative Commons Attribution-NonCommercial 3.0 Unported
Title: | Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation |
Authors: | Harada, Yae Browse this author | Hirata, Kenji Browse this author →KAKEN DB | Nakayama, Naoki Browse this author →KAKEN DB | Yamaguchi, Shigeru Browse this author | Yoshida, Michiharu Browse this author | Onodera, Shunsuke Browse this author | Manabe, Osamu Browse this author →KAKEN DB | Shiga, Tohru Browse this author →KAKEN DB | Terae, Satoshi Browse this author →KAKEN DB | Shirato, Hiroki Browse this author →KAKEN DB | Tamaki, Nagara Browse this author →KAKEN DB |
Keywords: | Intracranial arteriovenous malformation | stereotactic radiosurgery | radiation-induced necrosis | brain edema | F-18 fluorodeoxyglucose | positron emission tomography |
Issue Date: | 29-Jun-2015 |
Publisher: | SAGE Publications |
Journal Title: | Acta radiologica open |
Volume: | 4 |
Issue: | 6 |
Start Page: | 2058460115584112 |
Publisher DOI: | 10.1177/2058460115584112 |
Abstract: | A 55-year-old woman underwent radiosurgery for a left cerebral hemisphere arteriovenous malformation (AVM) and developed radiation-induced necrosis causing a massive edema in the surrounding brain tissues. Despite various therapies, the edema expanded to the ipsilateral hemisphere and induced neurological symptoms. The radiation-induced necrotic lesion was surgically removed 4 years after radiosurgery. While the preoperative FDG PET revealed severe hypometabolism in the left cerebrum, the necrotomy significantly ameliorated the brain edema, glucose metabolism (postoperative FDG PET), and symptoms. This case indicates that radiation necrosis-induced neurological deficits may be associated with brain edema and hypometabolism, which could be reversed by appropriate necrotomy. |
Rights: | http://creativecommons.org/licenses/by-nc/3.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/60585 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 平田 健司
|