|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion
Title: | Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion |
Authors: | Sakashita, Tomohiro Browse this author →KAKEN DB | Hayashi, Ryuichi Browse this author | Homma, Akihiro Browse this author →KAKEN DB | Matsuura, Kazuto Browse this author →KAKEN DB | Kato, Kengo Browse this author →KAKEN DB | Kawabata, Kazuyoshi Browse this author | Monden, Nobuya Browse this author | Hasegawa, Yasuhisa Browse this author →KAKEN DB | Onitsuka, Tetsuro Browse this author | Fujimoto, Yasushi Browse this author →KAKEN DB | Iwae, Shigemichi Browse this author | Okami, Kenji Browse this author →KAKEN DB | Matsuzuka, Takashi Browse this author →KAKEN DB | Yoshino, Kunitoshi Browse this author | Fujii, Masato Browse this author →KAKEN DB |
Keywords: | maxillary sinus cancer | orbital invasion | ocular function | squamous cell carcinoma | chemoradiotherapy |
Issue Date: | Apr-2015 |
Publisher: | Wiley |
Journal Title: | Head & Neck |
Volume: | 37 |
Issue: | 4 |
Start Page: | 537 |
End Page: | 542 |
Publisher DOI: | 10.1002/hed.23639 |
PMID: | 24715544 |
Abstract: | Background. This study aimed to evaluate ocular function and survival rates among treatment modalities in patients with maxillary sinus cancer with orbital invasion. Methods. Eighty-seven patients were classified according to the main treatment modality. Ocular function preservation rates and survival rates were evaluated for each therapeutic modality. Results. The 5-year overall survival rate for the en bloc resection, conservative surgery, superselective intra-arterial chemotherapy and radiotherapy (RADPLAT), intra-venous chemoradiotherapy (IV-CRT) was 70%, 35%, 49%, and 31%, respectively. Ocular function preservation rate for each group was 15%, 27%, 30%, and 17%, respectively. In the en bloc resection group, there was no significant difference in the 5-year overall survival rate between patients with orbital exenteration and those without orbital exenteration (72% vs 71%, p=0.9321). Conclusions. The en bloc resection group showed a favorable survival rate, but a low preservation rate. Preservation of orbital contents did not reduce the survival rate. |
Rights: | This is the peer reviewed version of the following article: Sakashita, T., Hayashi, R., Homma, A., Matsuura, K., Kato, K., Kawabata, K., Monden, N., Hasegawa, Y., Onitsuka, T., Fujimoto, Y., Iwae, S., Okami, K., Matsuzuka, T., Yoshino, K. and Fujii, M. (2015), Multi-institutional retrospective study for the evaluation of ocular function–preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion. Head Neck, 37: 537–542, which has been published in final form at http://doi.org/10.1002/hed.23639. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving: http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/61134 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 坂下 智博
|