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Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/61134

Title: Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion
Authors: Sakashita, Tomohiro Browse this author →KAKEN DB
Hayashi, Ryuichi Browse this author
Homma, Akihiro Browse this author →KAKEN DB
Matsuura, Kazuto Browse this author →KAKEN DB
Kato, Kengo Browse this author →KAKEN DB
Kawabata, Kazuyoshi Browse this author
Monden, Nobuya Browse this author
Hasegawa, Yasuhisa Browse this author →KAKEN DB
Onitsuka, Tetsuro Browse this author
Fujimoto, Yasushi Browse this author →KAKEN DB
Iwae, Shigemichi Browse this author
Okami, Kenji Browse this author →KAKEN DB
Matsuzuka, Takashi Browse this author →KAKEN DB
Yoshino, Kunitoshi Browse this author
Fujii, Masato Browse this author →KAKEN DB
Keywords: maxillary sinus cancer
orbital invasion
ocular function
squamous cell carcinoma
chemoradiotherapy
Issue Date: Apr-2015
Publisher: Wiley
Journal Title: Head & Neck
Volume: 37
Issue: 4
Start Page: 537
End Page: 542
Publisher DOI: 10.1002/hed.23639
PMID: 24715544
Abstract: Background. This study aimed to evaluate ocular function and survival rates among treatment modalities in patients with maxillary sinus cancer with orbital invasion. Methods. Eighty-seven patients were classified according to the main treatment modality. Ocular function preservation rates and survival rates were evaluated for each therapeutic modality. Results. The 5-year overall survival rate for the en bloc resection, conservative surgery, superselective intra-arterial chemotherapy and radiotherapy (RADPLAT), intra-venous chemoradiotherapy (IV-CRT) was 70%, 35%, 49%, and 31%, respectively. Ocular function preservation rate for each group was 15%, 27%, 30%, and 17%, respectively. In the en bloc resection group, there was no significant difference in the 5-year overall survival rate between patients with orbital exenteration and those without orbital exenteration (72% vs 71%, p=0.9321). Conclusions. The en bloc resection group showed a favorable survival rate, but a low preservation rate. Preservation of orbital contents did not reduce the survival rate.
Rights: This is the peer reviewed version of the following article: Sakashita, T., Hayashi, R., Homma, A., Matsuura, K., Kato, K., Kawabata, K., Monden, N., Hasegawa, Y., Onitsuka, T., Fujimoto, Y., Iwae, S., Okami, K., Matsuzuka, T., Yoshino, K. and Fujii, M. (2015), Multi-institutional retrospective study for the evaluation of ocular function–preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion. Head Neck, 37: 537–542, which has been published in final form at http://doi.org/10.1002/hed.23639. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving: http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms
Type: article (author version)
URI: http://hdl.handle.net/2115/61134
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 坂下 智博

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