Title: | Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors |
Authors: | Wang, Lei Browse this author |
Yoshida, Takuma Browse this author |
Muto, Yasuyuki Browse this author |
Murai, Yuta Browse this author |
Tachrim, Zetryana Puteri Browse this author |
Ishida, Akiko Browse this author |
Nakagawa, Shiori Browse this author |
Sakihama, Yasuko Browse this author →KAKEN DB |
Hashidoko, Yasuyuki Browse this author →KAKEN DB |
Masuda, Katsuyoshi Browse this author →KAKEN DB |
Hatanaka, Yasumaru Browse this author →KAKEN DB |
Hashimoto, Makoto Browse this author →KAKEN DB |
Keywords: | Synthetic methods |
Photoaffinity labeling |
Receptors |
Nitrogen heterocycles |
Saccharin |
Issue Date: | 18-May-2015 |
Publisher: | Wiley-Blackwell |
Journal Title: | European journal of organic chemistry |
Volume: | 14 |
Start Page: | 3129 |
End Page: | 3134 |
Publisher DOI: | 10.1002/ejoc.201500184 |
Abstract: | Saccharin is one of the most common artificial sweeteners that has a bitter taste at high concentrations. Currently, there are no detailed functional analyses of these gustatory receptors. Therefore, we designed and synthesized photoreactive saccharin derivatives that contain a (trifluoromethyl) diazirinyl moiety at the 5- or 6-position for use as functional analysis tools for photoaffinity labeling. |
Rights: | The right to self-archive the accepted and peer-reviewed(but not final) version of the Contribution on the Contributor’s personal website, in the Contributor’s company/institutional repository or archive, and in certain not for profit subject-based repositories such as PubMed Central, subject to an embargo period of 12 months following publication of the final Contribution. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/61529 |
Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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