| Title: | Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors |
| Authors: | Wang, Lei Browse this author |
| Yoshida, Takuma Browse this author |
| Muto, Yasuyuki Browse this author |
| Murai, Yuta Browse this author |
| Tachrim, Zetryana Puteri Browse this author |
| Ishida, Akiko Browse this author |
| Nakagawa, Shiori Browse this author |
| Sakihama, Yasuko Browse this author →KAKEN DB |
| Hashidoko, Yasuyuki Browse this author →KAKEN DB |
| Masuda, Katsuyoshi Browse this author →KAKEN DB |
| Hatanaka, Yasumaru Browse this author →KAKEN DB |
| Hashimoto, Makoto Browse this author →KAKEN DB |
| Keywords: | Synthetic methods |
| Photoaffinity labeling |
| Receptors |
| Nitrogen heterocycles |
| Saccharin |
| Issue Date: | 18-May-2015 |
| Publisher: | Wiley-Blackwell |
| Journal Title: | European journal of organic chemistry |
| Volume: | 14 |
| Start Page: | 3129 |
| End Page: | 3134 |
| Publisher DOI: | 10.1002/ejoc.201500184 |
| Abstract: | Saccharin is one of the most common artificial sweeteners that has a bitter taste at high concentrations. Currently, there are no detailed functional analyses of these gustatory receptors. Therefore, we designed and synthesized photoreactive saccharin derivatives that contain a (trifluoromethyl) diazirinyl moiety at the 5- or 6-position for use as functional analysis tools for photoaffinity labeling. |
| Rights: | The right to self-archive the accepted and peer-reviewed(but not final) version of the Contribution on the Contributor’s personal website, in the Contributor’s company/institutional repository or archive, and in certain not for profit subject-based repositories such as PubMed Central, subject to an embargo period of 12 months following publication of the final Contribution. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/61529 |
| Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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