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Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi

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Title: Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi
Authors: Kagawa, Yumiko Browse this author
Nakano, Yuko Browse this author
Kobayashi, Tetsuya Browse this author
Asano, Kazushi Browse this author
Takagi, Satoshi Browse this author →KAKEN DB
Keywords: histiocytic sarcoma
Pembroke Welsh Corgi
Issue Date: Dec-2015
Publisher: 公益社団法人 日本獣医学会
Journal Title: Journal of Veterinary Medical Science
Volume: 77
Issue: 12
Start Page: 1659
End Page: 1661
Publisher DOI: 10.1292/jvms.15-0284
Abstract: Nineteen cases of histiocytic sarcomas in Pembroke Welsh Corgi were examined histopathologically. Focal or multiple masses were detected in the lung or in regional lymph nodes, or in both lung and nodes. All neoplastic lesions had common histological features characterized by the proliferation of pleomorphic histiocytic cells combined with various inflammatory cells. Most of the pleomorphic neoplastic cells were immunopositive for human leukocyte antigen (HLA)-DR and Iba-1. The median survival time for all dogs was 133 days. In the present study, several prognostic factors, such as gender, age, single or multiple lesions, lymph node involvement at the time of diagnosis, surgical resection status and additional chemotherapy, were examined, although none of these factors approached statistical significance. Histiocytic sarcoma must be considered in the differential diagnosis of dogs with pulmonary masses, especially in the canine breed.
Type: article
Appears in Collections:獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 高木 哲

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