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Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi
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Title: | Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi |
Authors: | Kagawa, Yumiko Browse this author | Nakano, Yuko Browse this author | Kobayashi, Tetsuya Browse this author | Asano, Kazushi Browse this author | Takagi, Satoshi Browse this author →KAKEN DB |
Keywords: | histiocytic sarcoma | lung | Pembroke Welsh Corgi |
Issue Date: | Dec-2015 |
Publisher: | 公益社団法人 日本獣医学会 |
Journal Title: | Journal of Veterinary Medical Science |
Volume: | 77 |
Issue: | 12 |
Start Page: | 1659 |
End Page: | 1661 |
Publisher DOI: | 10.1292/jvms.15-0284 |
Abstract: | Nineteen cases of histiocytic sarcomas in Pembroke Welsh Corgi were examined histopathologically. Focal or multiple masses were detected in the lung or in regional lymph nodes, or in both lung and nodes. All neoplastic lesions had common histological features characterized by the proliferation of pleomorphic histiocytic cells combined with various inflammatory cells. Most of the pleomorphic neoplastic cells were immunopositive for human leukocyte antigen (HLA)-DR and Iba-1. The median survival time for all dogs was 133 days. In the present study, several prognostic factors, such as gender, age, single or multiple lesions, lymph node involvement at the time of diagnosis, surgical resection status and additional chemotherapy, were examined, although none of these factors approached statistical significance. Histiocytic sarcoma must be considered in the differential diagnosis of dogs with pulmonary masses, especially in the canine breed. |
Rights: | https://creativecommons.org/licenses/by-nc-nd/3.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/62287 |
Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 高木 哲
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