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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Life Science / Faculty of Advanced Life Science >
Peer-reviewed Journal Articles, etc >
Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration
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| Title: | Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration |
| Authors: | Nonoyama, Takayuki Browse this author | | Wada, Susumu Browse this author | | Kiyama, Ryuji Browse this author | | Kitamura, Nobuto Browse this author | | Mredha, Md.Tariful Islam Browse this author | | Zhang, Xi Browse this author | | Kurokawa, Takayuki Browse this author | | Nakajima, Tasuku Browse this author | | Takagi, Yasuaki Browse this author | | Yasuda, Kazunori Browse this author | | Gong, Jian Ping Browse this author →KAKEN DB |
| Keywords: | biomaterials | | double-network hydrogels | | hydroxyapatite | | osteointegration | | semi-permeability |
| Issue Date: | 17-Aug-2016 |
| Publisher: | Wiley-Blackwell |
| Journal Title: | Advanced Materials |
| Volume: | 28 |
| Issue: | 31 |
| Start Page: | 6740 |
| End Page: | 6745 |
| Publisher DOI: | 10.1002/adma.201601030 |
| PMID: | 27184968 |
| Abstract: | Implanting hydroxyapatite-mineralized tough hydrogel into osteochondral defects of rabbits, osteogenesis spontaneously penetrates into the gel matrix owing to the semi-permeablility of the hydrogel. The gradient layer (around 40 μm thick) contributes quite strong bonding of the gel to bone. This is the first success in realizing the robust osteointegration of tough hydrogels, and the method is simple and feasible for practical use. |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/62686 |
| Appears in Collections: | 生命科学院・先端生命科学研究院 (Graduate School of Life Science / Faculty of Advanced Life Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 龔 剣萍 (Gong Jian Ping)
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