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Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/62686

Title: Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration
Authors: Nonoyama, Takayuki Browse this author
Wada, Susumu Browse this author
Kiyama, Ryuji Browse this author
Kitamura, Nobuto Browse this author
Mredha, Md.Tariful Islam Browse this author
Zhang, Xi Browse this author
Kurokawa, Takayuki Browse this author
Nakajima, Tasuku Browse this author
Takagi, Yasuaki Browse this author
Yasuda, Kazunori Browse this author
Gong, Jian Ping Browse this author →KAKEN DB
Keywords: biomaterials
double-network hydrogels
hydroxyapatite
osteointegration
semi-permeability
Issue Date: 17-Aug-2016
Publisher: Wiley-Blackwell
Journal Title: Advanced Materials
Volume: 28
Issue: 31
Start Page: 6740
End Page: 6745
Publisher DOI: 10.1002/adma.201601030
PMID: 27184968
Abstract: Implanting hydroxyapatite-mineralized tough hydrogel into osteochondral defects of rabbits, osteogenesis spontaneously penetrates into the gel matrix owing to the semi-permeablility of the hydrogel. The gradient layer (around 40 μm thick) contributes quite strong bonding of the gel to bone. This is the first success in realizing the robust osteointegration of tough hydrogels, and the method is simple and feasible for practical use.
Rights: http://creativecommons.org/licenses/by-nc-nd/4.0/
Type: article
URI: http://hdl.handle.net/2115/62686
Appears in Collections:生命科学院・先端生命科学研究院 (Graduate School of Life Science / Faculty of Advanced Life Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 龔 剣萍 (Gong Jian Ping)

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