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The cardiac blood supply-workload balance in children

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タイトル: The cardiac blood supply-workload balance in children
著者: Murakami, Tomoaki 著作を一覧する
Takeda, Atsuhito 著作を一覧する
Takei, Kohta 著作を一覧する
Tateno, Shigeru 著作を一覧する
Kawasoe, Yasutaka 著作を一覧する
Niwa, Koichiro 著作を一覧する
キーワード: Aging
Growth
Aortic function
Central hemodynamics
発行日: 2015年 9月
出版者: Springer
誌名: Heart and vessels
巻: 30
号: 5
開始ページ: 626
終了ページ: 631
出版社 DOI: 10.1007/s00380-014-0537-0
抄録: It is well known that the reflected pressure wave in small children returns earlier than that in adolescent. The reason of early return of the reflected pressure wave in infancy is their height. The short distance between heart and reflection point makes the reflected pressure wave returning to the heart earlier. In adult, the early return (during systole) of the reflected pressure wave means disadvantage to cardiac blood supply-workload balance. The purpose of this study was to clarify whether the early return of the reflected pressure wave in small children impairs the cardiac blood supply-workload balance. This study enrolled 37 small left-to-right shunt patients with normal aortic circulation below 15 years of age. The aortic pressure waveform was recorded using a pressure sensor mounted catheter, and augmentation index and subendocardial viability ratio were calculated. The age of patients was 6.1 ± 3.2 years. The augmentation index was 8.7 ± 14.3 % and the index had a negative correlation with patients' age (r = -0.6243, p < 0.0001). The subendocardial viability ratio, which means the cardiac blood supply-workload balance, was 0.92 ± 0.14 and the index had a positive relationship with patients' age (r = 0.6435, p < 0.0001). The cardiac blood supply-workload balance gradually improves from infancy to young adulthood. One of the causes of the unfavorable cardiac blood supply-workload balance in infancy would be the accelerated aortic pressure wave reflection due to their short height.
Rights: The final publication is available at Springer via http://dx.doi.org/10.1007/s00380-014-0537-0
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/62738
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 武田 充人

 

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