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Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus : A single institution experience

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タイトル: Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus : A single institution experience
著者: Homma, Akihiro 著作を一覧する
Nakamaru, Yuji 著作を一覧する
Sakashita, Tomohiro 著作を一覧する
Onimaru, Rikiya 著作を一覧する
Terasaka, Shunsuke 著作を一覧する
Tsuchiya, Kazuhiko 著作を一覧する
Yoshida, Daisuke 著作を一覧する
Yasuda, Koichi 著作を一覧する
Hatakeyama, Hiromitsu 著作を一覧する
Furusawa, Jun 著作を一覧する
Mizumachi, Takatsugu 著作を一覧する
Kano, Satoshi 著作を一覧する
Shirato, Hiroki 著作を一覧する
Fukuda, Satoshi 著作を一覧する
キーワード: Nasal cavity
Ethmoid sinus
Squamous cell carcinoma
Surgery
Endoscopic
Radiation therapy
Chemotherapy
発行日: 2015年10月
出版者: Elsevier
誌名: Auris nasus larynx
巻: 42
号: 5
開始ページ: 377
終了ページ: 381
出版社 DOI: 10.1016/j.anl.2015.02.005
抄録: Objective: Here we report our experience of patients with squamous cell carcinoma (SCC) of the nasal cavity and ethmoid sinus (NC&ES) together with an analysis of treatment outcomes. Methods: A retrospective analysis was performed using data from 25 consecutive patients treated between 2000 and 2012. Four patients were diagnosed with T1, 3 with T2, 4 with T3, 7 with T4a, and 7 with T4b disease. No patient had lymph node metastasis. Results: Twelve patients were treated with surgery with/without radiotherapy and with/without chemotherapy. Of these, 4 underwent endoscopic surgery without an open approach and 3 required an anterior skull base approach. Thirteen were treated with radiotherapy; 1 with radiotherapy alone, and 4 and 8 with intravenous and intra-arterial chemotherapy, respectively. The 5-yr overall survival for T1-3, T4a, and T4b disease was 53.9%, 71.4%, and 29.0%, respectively. The 5-yr disease-specific survival for T1-3, T4a, and T4b disease was 74.1%, 71.4%, and 29.0%, respectively. Conclusion: Our treatment policy for patients with SCC of NC&ES, which basically follows the NCCN guideline, was considered to be appropriate. However, several points in terms of surgery and nonsurgical approach remain to be solved through further research.
Rights: © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/62918
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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