Title: | Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus : A single institution experience |
Authors: | Homma, Akihiro Browse this author →KAKEN DB |
Nakamaru, Yuji Browse this author →KAKEN DB |
Sakashita, Tomohiro Browse this author →KAKEN DB |
Onimaru, Rikiya Browse this author →KAKEN DB |
Terasaka, Shunsuke Browse this author →KAKEN DB |
Tsuchiya, Kazuhiko Browse this author →KAKEN DB |
Yoshida, Daisuke Browse this author |
Yasuda, Koichi Browse this author →KAKEN DB |
Hatakeyama, Hiromitsu Browse this author →KAKEN DB |
Furusawa, Jun Browse this author |
Mizumachi, Takatsugu Browse this author →KAKEN DB |
Kano, Satoshi Browse this author →KAKEN DB |
Shirato, Hiroki Browse this author →KAKEN DB |
Fukuda, Satoshi Browse this author →KAKEN DB |
Keywords: | Nasal cavity |
Ethmoid sinus |
Squamous cell carcinoma |
Surgery |
Endoscopic |
Radiation therapy |
Chemotherapy |
Issue Date: | Oct-2015 |
Publisher: | Elsevier |
Journal Title: | Auris nasus larynx |
Volume: | 42 |
Issue: | 5 |
Start Page: | 377 |
End Page: | 381 |
Publisher DOI: | 10.1016/j.anl.2015.02.005 |
PMID: | 25748513 |
Abstract: | Objective: Here we report our experience of patients with squamous cell carcinoma (SCC) of the nasal cavity and ethmoid sinus (NC&ES) together with an analysis of treatment outcomes. Methods: A retrospective analysis was performed using data from 25 consecutive patients treated between 2000 and 2012. Four patients were diagnosed with T1, 3 with T2, 4 with T3, 7 with T4a, and 7 with T4b disease. No patient had lymph node metastasis. Results: Twelve patients were treated with surgery with/without radiotherapy and with/without chemotherapy. Of these, 4 underwent endoscopic surgery without an open approach and 3 required an anterior skull base approach. Thirteen were treated with radiotherapy; 1 with radiotherapy alone, and 4 and 8 with intravenous and intra-arterial chemotherapy, respectively. The 5-yr overall survival for T1-3, T4a, and T4b disease was 53.9%, 71.4%, and 29.0%, respectively. The 5-yr disease-specific survival for T1-3, T4a, and T4b disease was 74.1%, 71.4%, and 29.0%, respectively. Conclusion: Our treatment policy for patients with SCC of NC&ES, which basically follows the NCCN guideline, was considered to be appropriate. However, several points in terms of surgery and nonsurgical approach remain to be solved through further research. |
Rights: | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/62918 |
Appears in Collections: | 国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc) 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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