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Synthesis of Cross-linkable 2,5-Diketopiperazine Derivatives

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Title: Synthesis of Cross-linkable 2,5-Diketopiperazine Derivatives
Authors: Yoshida, Takuma Browse this author
Wang, Lei Browse this author
Nakagawa, Shiori Browse this author
Tachrim, Zetryana Puteri Browse this author
Sakihama, Yasuko Browse this author →KAKEN DB
Hashidoko, Yasuyuki Browse this author →KAKEN DB
Hashimoto, Makoto Browse this author →KAKEN DB
Keywords: Cross-link
cyclic dipeptide
photoaffinity label
Issue Date: Oct-2015
Publisher: Bentham Science Publishers
Journal Title: Letters in organic chemistry
Volume: 12
Issue: 8
Start Page: 544
End Page: 548
Publisher DOI: 10.2174/1570178612666150629181357
Abstract: Synthesis of cross-linkable diketopiperadine derivatives is described. Cross-linkable a-amino acid methyl esters were subjected to peptide synthesis with Boc-protected glycine or L-tyrosine. No protection of cross-linkable functional groups (catechol and phenylazide) is necessary for the construction of diketopiperazine skeleton.
Rights: The published manuscript is available at EurekaSelect via
Type: article (author version)
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本 誠

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