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Decreased baseline variability on fetal heart rate pattern in a fetus with heterotaxy syndrome

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Title: Decreased baseline variability on fetal heart rate pattern in a fetus with heterotaxy syndrome
Authors: Yamada, Ryutaro Browse this author
Takei, Kohta Browse this author
Kaneshi, Yosuke Browse this author
Morikawa, Mamoru Browse this author →KAKEN DB
Cho, Kazutoshi Browse this author →KAKEN DB
Minakami, Hisanori Browse this author →KAKEN DB
Keywords: cardiotocogram
congenital cardiac malformation
fetal arrhythmia
fetal heart rate pattern
isomerism
Issue Date: Dec-2015
Publisher: Wiley-Blackwell
Journal Title: Journal of obstetrics and gynaecology research
Volume: 41
Issue: 12
Start Page: 1988
End Page: 1990
Publisher DOI: 10.1111/jog.12824
PMID: 26421346
Abstract: In a fetus with suspected heterotaxy syndrome, a decreased/absent baseline variability of fetal heart rate pattern developed at gestational week 36(+5) and continued for 5 days until birth at gestational week 37(+2), while repeat biophysical profile scorings with ultrasound were consistently unremarkable. This neonate weighing 2404 g with Apgar scores of 7 (1-min) and 8 (5-min) and umbilical arterial cord blood pH of 7.28 with base deficit of 3.9mmol/L, showed a heart rate of 120 b.p.m. for 3 h after birth, but subsequently developed sinus bradycardia (84 b.p.m.) unresponsive to crying. Isoproterenol initiated 9 h after birth was effective in the increase of heart rate to 120 b.p.m. in this neonate. Brain magnetic resonance imaging at 16 days of age was unremarkable. The decreased/absent baseline variability of fetal heart rate pattern was speculated to have been caused by sinus node dysfunction, and not by reduced fetal oxygenation in this case.
Rights: This is the peer reviewed version of the following article: Yamada, R., Takei, K., Kaneshi, Y., Morikawa, M., Cho, K., and Minakami, H. (2015) Decreased baseline variability on fetal heart rate pattern in a fetus with heterotaxy syndrome. J. Obstet. Gynaecol. Res., 41: 1988–1990., which has been published in final form at http://dx.doi.org/10.1111/jog.12824. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Type: article (author version)
URI: http://hdl.handle.net/2115/63711
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 水上 尚典

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