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Fatal cardiac small-vessel involvement in ANCA-associated vasculitis: an autopsy case report


Cardiovasc Pathol 2015.pdf184.96 kBPDF見る/開く

タイトル: Fatal cardiac small-vessel involvement in ANCA-associated vasculitis: an autopsy case report
著者: Iwasaki, Sari 著作を一覧する
Suzuki, Akira 著作を一覧する
Fujisawa, Takashi 著作を一覧する
Sato, Taiju 著作を一覧する
Shirai, Shinya 著作を一覧する
Kamigaki, Mitsunori 著作を一覧する
Otsuka, Noriyuki 著作を一覧する
Tomaru, Utano 著作を一覧する
Ishizu, Akihiro 著作を一覧する
キーワード: ANCA-associated vasculitis
Cardiac small-vessel involvement
Sudden death
発行日: 2015年11月
出版者: Elsevier
誌名: Cardiovascular Pathology
巻: 24
号: 6
開始ページ: 408
終了ページ: 410
出版社 DOI: 10.1016/j.carpath.2015.07.005
抄録: An 80-year-old Japanese man, who had fever and generalized fatigue not improved by antibiotics, was admitted to our hospital. Laboratory data indicative of renal dysfunction and antineutrophil cytoplasmic antibody (ANCA) in the serum led to the consideration of ANCA-associated vasculitis as a differential diagnosis. However, before the diagnostic confirmation, he was found dead on the bed. Autopsy revealed necrotizing crescentic glomerulonephritis in the kidneys. In addition, necrotizing granulomatous vasculitis with infiltration of multinucleated giant cells and neutrophils but not eosinophils was present in multiple organs. The direct cause of death was presumed as cardiac arrest by lethal arrhythmia because vasculitic lesions were distributed widely in the cardiac walls, acute congestion was observed in the systemic organs, and other causes of death were ruled out. This report presents the unusual manifestation of cardiac small-vessel involvement in ANCA-associated vasculitis related to sudden death.
Rights: ©2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 石津 明洋


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