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Estimating the subcritical transmissibility of the Zika outbreak in the State of Florida, USA, 2016

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Title: Estimating the subcritical transmissibility of the Zika outbreak in the State of Florida, USA, 2016
Authors: Dinh, Linh Browse this author
Chowell, Gerardo Browse this author
Mizumoto, Kenji Browse this author
Nishiura, Hiroshi Browse this author →KAKEN DB
Keywords: Prediction
Zika virus
Mathematical model
Basic reproduction number
Issue Date: 9-Nov-2016
Publisher: BioMed Central
Journal Title: Theoretical biology and medical modelling
Volume: 13
Start Page: 20
Publisher DOI: 10.1186/s12976-016-0046-1
Abstract: Background: Florida State has reported autochthonous transmission of Zika virus since late July 2016. Here we assessed the transmissibility associated with the outbreak and generated a short-term forecast. Methods: Time-dependent dynamics of imported cases reported in the state of Florida was approximated by a logistic growth equation. We estimated the reproduction number using the renewal equation in order to predict the incidence of local cases arising from both local and imported primary cases. Using a bootstrap method together with the logistic and renewal equations, a short-term forecast of local and imported cases was carried out. Results: The reproduction number was estimated at 0.16 (95 % Confidence Interval: 0.13, 0.19). Employing the logistic equation to capture a drastic decline in the number of imported cases expected through the course of 2016, together with the low estimate of the local reproduction number in Florida, the expected number of local reported cases was demonstrated to show an evident declining trend for the remainder of 2016. Conclusions: The risk of local transmission in the state of Florida is predicted to dramatically decline by the end of 2016.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 西浦 博

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