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Radiographic quantifications of joint space narrowing progression by computer-based approach using temporal subtraction in rheumatoid wrist

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/64398

Title: Radiographic quantifications of joint space narrowing progression by computer-based approach using temporal subtraction in rheumatoid wrist
Authors: Ichikawa, Shota Browse this author
Kamishima, Tamotsu Browse this author →KAKEN DB
Sutherland, Kenneth Browse this author →KAKEN DB
Okubo, Takanobu Browse this author
Katayama, Kou Browse this author
Issue Date: Jan-2016
Publisher: British Institute of Radiology
Journal Title: British journal of radiology
Volume: 89
Issue: 1057
Start Page: 20150403
Publisher DOI: 10.1259/bjr.20150403
PMID: 26481695
Abstract: Objective: To investigate the validity of a computerbased method using temporal subtraction in carpal joints of patients with rheumatoid arthritis (RA), which can detect the difference in joint space between two images with the joint space difference index (JSDI). Methods: The study consisted of 43 patients with RA (39 females and 4 males) who underwent radiography at baseline and at 1-year follow-up. The joint space narrowing (JSN) of carpal joints on bilateral hand radiographs was assessed by our computer-based method, using the Sharp/ van der Heijde method as the standard of reference. We compared the JSDI of joints with JSN progression in the follow-up period with that of those without JSN progression. In addition, we examined whether there is a significant difference in JSDI in terms of laterality or topology of the joint. Results: The JSDI of joints with JSN progression was significantly higher than that of those without JSN progression (Mann-Whitney U test, p < 0.001). There was no statistically significant difference in the JSDI between the left and right carpal joints, which was analysed for five different joints altogether and each joint separately (Mann-Whitney U test, p > 0.05). There was statistically significant difference in JSDI among different joints (Kruskal-Wallis test, p = 0.003). Conclusion: These results suggest that our computerbased method may be useful to recognize the JSN progression on radiographs of rheumatoid wrists. Advances in knowledge: The computer-based temporal subtraction method can detect the JSN progression in the wrist, which is the single most commonly involved site in RA.
Relation: http://www.birpublications.org/toc/bjr/current
Type: article (author version)
URI: http://hdl.handle.net/2115/64398
Appears in Collections:保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 神島 保

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