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Trends and determinant factors in the use of cardiac resynchronization therapy devices in Japan : Analysis of the Japan cardiac device treatment registry database

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タイトル: Trends and determinant factors in the use of cardiac resynchronization therapy devices in Japan : Analysis of the Japan cardiac device treatment registry database
著者: Yokoshiki, Hisashi 著作を一覧する
Shimizu, Akihiko 著作を一覧する
Mitsuhashi, Takeshi 著作を一覧する
Furushima, Hiroshi 著作を一覧する
Sekiguchi, Yukio 著作を一覧する
Manaka, Tetsuyuki 著作を一覧する
Nishii, Nobuhiro 著作を一覧する
Ueyama, Takeshi 著作を一覧する
Morita, Norishige 著作を一覧する
Nitta, Takashi 著作を一覧する
Okumura, Ken 著作を一覧する
キーワード: Cardiac resynchronization therapy
Defibrillator
Primary prevention
Heart failure
発行日: 2016年12月
出版者: Elsevier
誌名: Journal of arrhythmia
巻: 32
号: 6
開始ページ: 486
終了ページ: 490
出版社 DOI: 10.1016/j.joa.2016.04.002
抄録: Background: The choice of cardiac resynchronization therapy device, with (CRT-D) or without (CRT-P) a defibrillator, in patients with heart failure largely depends on the physician's discretion, because it has not been established which subjects benefit most from a defibrillator. Methods: We examined the annual trend of CRT device implantations between 2006 and 2014, and evaluated the factors related to the device selection (CRT-D or CRT-P) for primary prevention of sudden cardiac death in patients with heart failure by analyzing the Japan Cardiac Device Treatment Registry (JCDTR) database from January 2011 and August 2015 (CRT-D, n=2714; CRT-P, n=555). Results: The proportion of CRT-D implantations for primary prevention among all the CRT-D recipients was more than 70% during the study period. The number of CRT-D implantations for primary prevention reached a maximum in 2011 and decreased gradually between 2011 and 2014, whereas CRT-P implantations increased year by year until 2011 and remained unchanged in recent years. Multivariate analysis identified age (odds ratio [OR] 0.92, 95% confidence interval [CI] 0.90-0.95, P < 0.0001), male sex (OR 1.99, 95% CI 1.28-3.11, P < 0.005), reduced left ventricular ejection fraction (LVEF) (OR 0.96, 95% CI 0.94-0.98, P < 0.0001), and non-sustained ventricular tachycardia (NSVT) (OR 2.85, 95% CI 1.87-4.35, P < 0.0001) as independent factors favoring the choice of CRT-D. Conclusions: Younger age, male sex, reduced LVEF, and a history of NSVT were independently associated with the choice of CRT-D for primary prevention of sudden cardiac death in patients with heart failure in Japan.
資料タイプ: article
URI: http://hdl.handle.net/2115/64758
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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