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Recent Progress in Diazirine-Based Photoaffinity Labeling

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Title: Recent Progress in Diazirine-Based Photoaffinity Labeling
Authors: Hashimoto, Makoto Browse this author →KAKEN DB
Hatanaka, Yasumaru Browse this author
Keywords: Photoaffinity labeling
Chemical biology
Bioorganic chemistry
Structure-activity relatonships
Issue Date: May-2008
Publisher: Wiley-VCH
Journal Title: European Journal of Organic Chemistry
Volume: 2008
Issue: 15
Start Page: 2513
End Page: 2523
Publisher DOI: 10.1002/ejoc.200701069
Abstract: Based on the recent development of molecular biology, the investigation of biofunctional machinery at their ligand accepting interface has become one of the challenging and important subject of post-genome field. The technique of photoaffinity labeling has become increasingly appreciated as a powerful methodology for the purpose. This micro review focused synthesis of trifluoromethylphenyldiazirine, which is one of the most promising photophore, and its application to the biomolecules.
Type: article (author version)
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本 誠

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