Recent Progress in Diazirine-Based Photoaffinity Labeling


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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/64901

Title:	Recent Progress in Diazirine-Based Photoaffinity Labeling
Authors:	Hashimoto, Makoto Browse this author →KAKEN DB
Authors:	Hatanaka, Yasumaru Browse this author
Keywords:	Photoaffinity labeling
	Chemical biology
	Bioorganic chemistry
	Structure-activity relatonships
	Diazirine
Issue Date:	May-2008
Publisher:	Wiley-VCH
Journal Title:	European Journal of Organic Chemistry
Volume:	2008
Issue:	15
Start Page:	2513
End Page:	2523
Publisher DOI:	10.1002/ejoc.200701069
Abstract:	Based on the recent development of molecular biology, the investigation of biofunctional machinery at their ligand accepting interface has become one of the challenging and important subject of post-genome field. The technique of photoaffinity labeling has become increasingly appreciated as a powerful methodology for the purpose. This micro review focused synthesis of trifluoromethylphenyldiazirine, which is one of the most promising photophore, and its application to the biomolecules.
Type:	article (author version)
URI:	http://hdl.handle.net/2115/64901
Appears in Collections:	農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本誠

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