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Asymmetric and efficient synthesis of homophenylalanine derivatives via Friedel–Crafts reaction with trifluoromethanesulfonic acid

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Title: Asymmetric and efficient synthesis of homophenylalanine derivatives via Friedel–Crafts reaction with trifluoromethanesulfonic acid
Authors: Murashige, Ryo Browse this author
Hayashi, Yuka Browse this author
Hashimoto, Makoto Browse this author →KAKEN DB
Keywords: homophenylalanine
Friedel-Crafts reaction
Issue Date: 10-Nov-2008
Publisher: Elsevier
Journal Title: Tetrahedron Letters
Volume: 49
Issue: 46
Start Page: 6566
End Page: 6568
Publisher DOI: 10.1016/j.tetlet.2008.09.013
Abstract: An efficient Friedel-Crafts reaction of TFA-Asp(Cl)-OMe and stoichiometric amounts of benzene was established by using neat trifluoromethanesulfonic acid (TfOH) as solvent and catalyst under a mild condition. This methodology has been applied to many aromatic compounds and enabled synthesis of several homophenylalanine derivatives.
Rights: © 2017 Elsevier Science
Type: article (author version)
URI: http://hdl.handle.net/2115/64916
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本 誠

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