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A novel biotinylated diazirinyl ceramide analogue for photoaffinity labeling

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Title: A novel biotinylated diazirinyl ceramide analogue for photoaffinity labeling
Authors: Hashimoto, Makoto Browse this author →KAKEN DB
Hatanaka, Yasumaru Browse this author
Keywords: Photoaffinity labeling
Issue Date: 15-Jan-2008
Publisher: Elsevier
Journal Title: Bioorganic & Medicinal Chemistry Letters
Volume: 18
Issue: 2
Start Page: 650
End Page: 652
Publisher DOI: 10.1016/j.bmcl.2007.11.071
Abstract: A novel photoreactive ceramide analogue, which contains (3-trifluoromethyl) phenyldiazirinyl lipid and biotinylated sphingosine, was synthesized. The probe was recognized as an antigen by anti-ceramide antibody and as a substrate for sphingolipid ceramide N-deacylase. These results indicate that the probe may be useful as a photoaffinity-biotinylating agent in sphingolipid studies.
Rights: © 2007 Elsevier Ltd
Type: article (author version)
URI: http://hdl.handle.net/2115/64917
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本 誠

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