A novel biotinylated diazirinyl ceramide analogue for photoaffinity labeling


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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/64917

Title:	A novel biotinylated diazirinyl ceramide analogue for photoaffinity labeling
Authors:	Hashimoto, Makoto Browse this author →KAKEN DB
Authors:	Hatanaka, Yasumaru Browse this author
Keywords:	Photoaffinity labeling
Issue Date:	15-Jan-2008
Publisher:	Elsevier
Journal Title:	Bioorganic & Medicinal Chemistry Letters
Volume:	18
Issue:	2
Start Page:	650
End Page:	652
Publisher DOI:	10.1016/j.bmcl.2007.11.071
Abstract:	A novel photoreactive ceramide analogue, which contains (3-trifluoromethyl) phenyldiazirinyl lipid and biotinylated sphingosine, was synthesized. The probe was recognized as an antigen by anti-ceramide antibody and as a substrate for sphingolipid ceramide N-deacylase. These results indicate that the probe may be useful as a photoaffinity-biotinylating agent in sphingolipid studies.
Rights:	© 2007 Elsevier Ltd
Type:	article (author version)
URI:	http://hdl.handle.net/2115/64917
Appears in Collections:	農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本誠

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