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Influenza 2014-2015 among pregnant Japanese women : primiparous vs multiparous women

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Title: Influenza 2014-2015 among pregnant Japanese women : primiparous vs multiparous women
Other Titles: Influenza in pregnancy
Authors: Yamada, T.1 Browse this author →KAKEN DB
Kawakami, S.2 Browse this author
Yoshida, Y.3 Browse this author
Kawamura, H.4 Browse this author
Ohta, S.5 Browse this author
Abe, K.6 Browse this author
Hamada, H.7 Browse this author →KAKEN DB
Dohi, S.8 Browse this author
Ichizuka, K.9 Browse this author →KAKEN DB
Takita, H.10 Browse this author
Baba, Y.11 Browse this author
Matsubara, S.12 Browse this author →KAKEN DB
Mochizuki, J.13 Browse this author
Unno, N.14 Browse this author
Maegawa, Y.15 Browse this author
Maeda, M.16 Browse this author
Inubashiri, E.17 Browse this author
Akutagawa, N.18 Browse this author
Kubo, T.19 Browse this author
Shirota, T.20 Browse this author
Oda, Y.21 Browse this author
Yamada, T.22 Browse this author →KAKEN DB
Yamagishi, E.23 Browse this author
Nakai, A.24 Browse this author →KAKEN DB
Fuchi, N.25 Browse this author
Masuzaki, H.26 Browse this author →KAKEN DB
Urabe, S.27 Browse this author
Kudo, Y.28 Browse this author →KAKEN DB
Nomizo, M.29 Browse this author
Sagawa, N.30 Browse this author →KAKEN DB
Maeda, T.31 Browse this author
Kamitomo, M.32 Browse this author
Kawabata, K.33 Browse this author
Kataoka, S.34 Browse this author →KAKEN DB
Shiozaki, A.35 Browse this author →KAKEN DB
Saito, S.36 Browse this author →KAKEN DB
Sekizawa, A.37 Browse this author →KAKEN DB
Minakami, H.38 Browse this author →KAKEN DB
Authors(alt): Yamada, Takahiro1
Kawakami, Shoichi2
Yoshida, Yushin3
Kawamura, Hiroshi4
Ohta, Shiyo5
Abe, Kanako6
Hamada, Hiromi7
Dohi, Satoshi8
Ichizuka, Kiyotake9
Takita, Hiroko10
Baba, Yosuke11
Matsubara, Shigeki12
Mochizuki, Junko13
Unno, Nobuya14
Maegawa, Yuka15
Maeda, Makoto16
Inubashiri, Eisuke17
Akutagawa, Noriyuki18
Kubo, Takahiko19
Shirota, Takuhiko20
Oda, Yasunari21
Yamada, Takashi22
Yamagishi, Emi23
Nakai, Akihito24
Fuchi, Naoki25
Masuzaki, Hideaki26
Urabe, Satoshi27
Kudo, Yoshiki28
Nomizo, Mari29
Sagawa, Norimasa30
Maeda, Takatsugu31
Kamitomo, Masato32
Kawabata, Kosuke33
Kataoka, Soromon34
Shiozaki, Arihiro35
Saito, Shigeru36
Sekizawa, Akihiko37
Minakami, Hisanori38
Keywords: influenza pandemic
influenza vaccine effectiveness
pregnancy and infection
Issue Date: Apr-2016
Publisher: Springer
Journal Title: European journal of clinical microbiology & infectious diseases
Volume: 35
Issue: 4
Start Page: 665
End Page: 671
Publisher DOI: 10.1007/s10096-016-2585-0
PMID: 26864040
Abstract: Objectives: This study was performed to determine whether multiparous pregnant women are prone to influenza. Methods: A questionnaire survey was conducted at 19 centres located throughout Japan, targeting all 6694 postpartum women within 7 days after birth before leaving the hospital. All women gave birth during the study period between March 1, 2015, and July 31, 2015. Data regarding vaccination and influenza infection in or after October 2014, age, previous experience of childbirth, and number and ages of cohabitants were collected. Results: Seventy-eight percent (n = 5,197) of women given questionnaires responded. Of these, 2,661 (51%) and 364 (7.0%) women reported having been vaccinated and having contracted influenza, respectively. Multiparous women had a higher risk of influenza regardless of vaccination status (8.9% [121/1,362] vs. 5.7% [74/1,299], relative risk [95% confidence interval], 1.80 [1.36 to 2.38] for vaccinated and 9.3% [112/1,198] vs. 4.3% [57/1,328], 2.18 [1.60 to 2.97] for unvaccinated women) compared to primiparous women. The risk of influenza increased with increasing number of cohabitants: 4.8% (100/2,089), 7.5%, (121/1,618), 9.0%, (71/785), and 10.4% (58/557) for women with 1, 2, 3, and ≥ 4 cohabitants, respectively. Conclusions: Family size is a risk factor for influenza infection in pregnancy.
Rights: The final publication is available at
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 山田 崇弘

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