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Sonographic findings of immunoglobulin G4-related sclerosing sialadenitis
| Title: | Sonographic findings of immunoglobulin G4-related sclerosing sialadenitis |
| Authors: | Omotehara, Satomi Browse this author | | Nishida, Mutsumi Browse this author →KAKEN DB | | Satoh, Megumi Browse this author | | Inoue, Mamiko Browse this author | | Kudoh, Yusuke Browse this author | | Horie, Tatsunori Browse this author | | Homma, Akihiro Browse this author →KAKEN DB | | Nakamaru, Yuji Browse this author →KAKEN DB | | Hatanaka, Kanako C. Browse this author | | Shimizu, Chikara Browse this author →KAKEN DB |
| Keywords: | Ultrasonography | | Immunoglobulin G4-related sclerosing sialadenitis | | Submandibular gland | | Diagnosis | | Doppler signaling |
| Issue Date: | Apr-2016 |
| Publisher: | Springer |
| Journal Title: | Journal of medical ultrasonics |
| Volume: | 43 |
| Issue: | 2 |
| Start Page: | 257 |
| End Page: | 262 |
| Publisher DOI: | 10.1007/s10396-015-0693-6 |
| PMID: | 26707999 |
| Abstract: | Purpose: We evaluated the sonographic findings of immunoglobulin G4-related sclerosing sialadenitis (IgG4-SS). Methods: Nineteen patients with IgG4-SS and 12 healthy volunteers (controls) were enrolled. The following sonographic features were evaluated: (1) enlargement of the submandibular gland by measurement of the longitudinal diameter and thickness; (2) the contour texture of the submandibular gland (smooth or rough); (3) the internal echo texture, categorized into three sonographic patterns (homogeneous, multiple hypoechoic nodule, and diffuse hypoechoic); and (4) quantitative color Doppler signaling. Results: The longitudinal diameter and the thickness (mean ± SD) of the submandibular gland were significantly greater in patients than in controls (p = 0.005 and p < 0.001, respectively). Contour roughness was seen in 62.9 and 8.3 % of patients and controls (p < 0.001), respectively. Homogeneous echo textures alone were seen in controls, whereas multiple hypoechoic nodule patterns were seen in 60 % of the patients, and diffuse hypoechoic patterns were seen in 40 %. Color Doppler signaling (mean ± SD) was significantly higher in patients as compared with controls (p < 0.001). Conclusion: Patients could be distinguished from healthy volunteers using four distinctive sonographic findings, suggesting that ultrasonography would be a useful diagnostic tool for IgG4-SS. |
| Rights: | The final publication is available at link.springer.com |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/64954 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 表原 里実
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