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A Case of Severe Panuveitis Associated with Psoriasis Vulgaris Successfully Treated with Infliximab
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| Title: | A Case of Severe Panuveitis Associated with Psoriasis Vulgaris Successfully Treated with Infliximab |
| Authors: | Sakurai, Yuri Browse this author | | Namba, Kenichi Browse this author →KAKEN DB | | Mizuuchi, Kazuomi Browse this author | | Nomura, Toshihumi Browse this author | | Ishida, Susumu Browse this author →KAKEN DB |
| Keywords: | Uveitis | | Psoriasis | | Neovascularization | | Infliximab |
| Issue Date: | Apr-2016 |
| Publisher: | Karger |
| Journal Title: | Case Reports in Ophthalmology |
| Volume: | 7 |
| Issue: | 1 |
| Start Page: | 191 |
| End Page: | 194 |
| Publisher DOI: | 10.1159/000445285 |
| Abstract: | Purpose: Uveitis associated with psoriasis vulgaris is usually seen as an anterior segment inflammation, and it is very rare that the inflammation extends to the posterior segment. We herein report a case of severe panuveitis associated with psoriasis vulgaris presenting as retinal neovascularization, leading to vitreous hemorrhages that were successfully treated with infliximab (IFX). Case Report: A 27-year-old male with psoriasis vulgaris was referred to our hospital due to prolonged severe uveitis OU. He showed a severe anterior chamber inflammation with fibrin formation and total posterior iris synechia OU. With topical corticosteroid treatment, these conditions were relieved for a short time; however, the intraocular inflammation was exacerbated with vitreous hemorrhages caused by retinal neovascularization OS. After the administration of IFX therapy, the intraocular inflammation and retinal neovascularization was resolved, and so far, no severe recurrences have been seen for 3 years with the therapy. Conclusion: When we see patients with severe panuveitis associated with psoriasis extending to the posterior segment, IFX treatment may be a good therapeutic option. |
| Rights: | The final, published version of this article is available at http://www.karger.com/?doi=10.1159/000445285 | | https://creativecommons.org/licenses/by-nc/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/65857 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 南場 研一
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