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A Case of Severe Panuveitis Associated with Psoriasis Vulgaris Successfully Treated with Infliximab

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Title: A Case of Severe Panuveitis Associated with Psoriasis Vulgaris Successfully Treated with Infliximab
Authors: Sakurai, Yuri Browse this author
Namba, Kenichi Browse this author →KAKEN DB
Mizuuchi, Kazuomi Browse this author
Nomura, Toshihumi Browse this author
Ishida, Susumu Browse this author →KAKEN DB
Keywords: Uveitis
Issue Date: Apr-2016
Publisher: Karger
Journal Title: Case Reports in Ophthalmology
Volume: 7
Issue: 1
Start Page: 191
End Page: 194
Publisher DOI: 10.1159/000445285
Abstract: Purpose: Uveitis associated with psoriasis vulgaris is usually seen as an anterior segment inflammation, and it is very rare that the inflammation extends to the posterior segment. We herein report a case of severe panuveitis associated with psoriasis vulgaris presenting as retinal neovascularization, leading to vitreous hemorrhages that were successfully treated with infliximab (IFX). Case Report: A 27-year-old male with psoriasis vulgaris was referred to our hospital due to prolonged severe uveitis OU. He showed a severe anterior chamber inflammation with fibrin formation and total posterior iris synechia OU. With topical corticosteroid treatment, these conditions were relieved for a short time; however, the intraocular inflammation was exacerbated with vitreous hemorrhages caused by retinal neovascularization OS. After the administration of IFX therapy, the intraocular inflammation and retinal neovascularization was resolved, and so far, no severe recurrences have been seen for 3 years with the therapy. Conclusion: When we see patients with severe panuveitis associated with psoriasis extending to the posterior segment, IFX treatment may be a good therapeutic option.
Rights: The final, published version of this article is available at
Type: article
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 南場 研一

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