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Dietary Patterns and Risk of Esophageal Cancer Mortality : The Japan Collaborative Cohort Study

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タイトル: Dietary Patterns and Risk of Esophageal Cancer Mortality : The Japan Collaborative Cohort Study
著者: Okada, Emiko 著作を一覧する
Nakamura, Koshi 著作を一覧する
Ukawa, Shigekazu 著作を一覧する
Sakata, Kiyomi 著作を一覧する
Date, Chigusa 著作を一覧する
Iso, Hiroyasu 著作を一覧する
Tamakoshi, Akiko 著作を一覧する
キーワード: dietary pattern
esophageal cancer
cohort study
epidemiological study
発行日: 2016年
出版者: Taylor & Francis
誌名: Nutrition and cancer
巻: 68
号: 6
開始ページ: 1001
終了ページ: 1009
出版社 DOI: 10.1080/01635581.2016.1192202
抄録: Several case-control studies have associated dietary patterns with esophageal cancer (EC) risk, but prospective studies are scarce. We investigated dietary pattern and EC mortality risk associations by smoking status. Participants were 26,562 40- to 79-yr-old Japanese men, who enrolled in the Japan Collaborative Cohort Study between 1988 and 1990. Hazard ratios (HRs) and 95% confidence intervals (CIs) for EC mortality in nonsmokers and smokers were estimated using Cox proportional models. During follow-up (1988-2009), 132 participants died of EC. Using a baseline food frequency questionnaire and factor analysis, vegetable, animal, and dairy product food patterns were identified. EC risk decreased significantly with a higher factor score for the dairy product pattern (Ptrend = 0.042) and was more pronounced in smokers [multivariable HR (4th vs. 1st quartiles) = 0.57, 95% CI: 0.30, 1.09; Ptrend = 0.021]. Neither vegetable nor animal food patterns were significant overall; however, EC risk increased with a higher factor score for the animal food pattern in nonsmokers [multivariable HR (4th vs. 1st quartiles) = 6.01, 95% CI: 1.17, 30.88; Ptrend = 0.021], although the small number of events was a limitation. Our findings suggest a dairy product pattern may reduce EC risk in Japanese men, especially smokers.
Rights: This is an Accepted Manuscript of an article published by Taylor & Francis in Nutrition and Cancer in 2016, available online:
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 岡田 恵美子


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