HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
触媒科学研究所  >
雑誌発表論文等  >

Synthesis of 2,5-disubstituted pyrroles via dehydrogenative condensation of secondary alcohols and 1,2-amino alcohols by supported platinum catalysts

フルテキスト
OCF-pyrroles.pdf312.65 kBPDF見る/開く
この文献へのリンクには次のURLを使用してください:http://hdl.handle.net/2115/66435

タイトル: Synthesis of 2,5-disubstituted pyrroles via dehydrogenative condensation of secondary alcohols and 1,2-amino alcohols by supported platinum catalysts
著者: Siddiki, S. M. A. H. 著作を一覧する
Touchy, Abeda S. 著作を一覧する
Chaudhari, Chandan 著作を一覧する
Kon, Kenichi 著作を一覧する
Toyao, Takashi 著作を一覧する
Shimizu, Ken-ichi 著作を一覧する
発行日: 2016年 7月 1日
出版者: RSC Publishing
誌名: Organic chemistry frontiers
巻: 3
号: 7
開始ページ: 846
終了ページ: 851
出版社 DOI: 10.1039/c6qo00165c
抄録: Direct synthesis of 2,5-disubstituted pyrroles has been achieved via acceptorless dehydrogenative heterocyclization of 1,2-aminoalcohols and secondary alcohols by utilizing a heterogeneous carbon-supported Pt catalyst (Pt/C). The optimized method gave 92% yield of 2-ethyl-5-phenyl-1H-pyrrole as a desired product from 2-amino-1-butanol and 1-phenylethanol in the presence of 0.1 mol% of Pt/C and 1.1 equiv. of KOtBu. It has been revealed that Pt/C demonstrates superior catalytic activity to a number of catalysts tested in this study including other transition metal-loaded carbon and various metal-oxide-supported Pt catalysts. In addition, the turnover number (TON) obtained in the present system was found to be higher than those obtained in previously-reported catalytic systems. It is significant that the Pt/C catalyst could be recycled as a heterogeneous catalyst without significant loss in the activity and showed a wide substrate scope for the 2,5-disubstituted pyrrole forming process.
Rights: © the Partner Organisations 2016
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/66435
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 清水 研一

 

本サイトに関するご意見・お問い合わせは repo at lib.hokudai.ac.jp へお願いします。 - 北海道大学