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Comparison of cardiac output measurements using transpulmonary thermodilution and conventional thermodilution techniques in anaesthetized dogs with fluid overload

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タイトル: Comparison of cardiac output measurements using transpulmonary thermodilution and conventional thermodilution techniques in anaesthetized dogs with fluid overload
著者: Itami, Takaharu 著作を一覧する
Endo, Yusuke 著作を一覧する
Hanazono, Kiwamu 著作を一覧する
Ishizuka, Tomohito 著作を一覧する
Tamura, Jun 著作を一覧する
Miyoshi, Kenjiro 著作を一覧する
Sano, Tadashi 著作を一覧する
Yamashita, Kazuto 著作を一覧する
キーワード: cardiac output
dog
fluid overload
thermodilution
transpulmonary
発行日: 2016年 7月
出版者: Wiley-Blackwell
誌名: Veterinary Anaesthesia and Analgesia
巻: 43
号: 4
開始ページ: 388
終了ページ: 396
出版社 DOI: 10.1111/vaa.12331
抄録: Objective: To evaluate the agreement between cardiac output (CO) values obtained using a transpulmonary thermodilution technique (TPTDCO) and conventional thermodilution technique (TDCO) in anaesthetized dogs with fluid overload. Study design: Prospective experimental study. Animals: Six healthy Beagle dogs aged 7-8years. Methods: Dogs were anaesthetized with sevoflurane in oxygen, and catheters were inserted for TPTDCO and TDCO measurement. After instrumentation, baseline CO was measured using each technique at a central venous pressure (CVP) of 3-7mmHg. Dogs were subsequently administered lactated Ringer's solution and 6% hydroxyethyl starch to induce fluid overload. CO measurements were obtained using each technique at CVP values of 8-12mmHg, 13-17mmHg, 18-22mmHg and 23-27mmHg. Agreements between CO measurements obtained with the respective techniques were analysed using Dunnett's test, Pearson's correlation coefficient and Bland-Altman analysis. Results: Thirty pairs of CO values were obtained, ranging from 1.45Lminute(-1) to 4.69Lminute(-1) for TPTDCO and from 1.30Lminute(-1) to 4.61Lminute(-1) for TDCO. TPTDCO and TDCO values correlated strongly (r(2)=0.915, p<0.001). The bias and mean relative bias between TPTDCO and TDCO were 0.260.30Lminute(-1) (limits of agreement -0.29 to 0.81Lminute(-1)) and 9.7%, respectively. Conclusions and clinical relevance: TPTDCO and TDCO measurements obtained in anaesthetized dogs during fluid overload exhibited good agreement. Accordingly, transpulmonary thermodilution provides an accurate measurement of CO in dogs with fluid overload.
Rights: This is the peer reviewed version of the following article: Itami T, Endo Y, Hanazono K et al. (2015) Comparison of cardiac output measurements using transpulmonary thermodilution and conventional thermodilution techniques in anaesthetized dogs with fluid overload. Vet Anaesth Analg 43, 388-396, which has been published in final form at http://dx.doi.org/10.1111/vaa.12331. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/66557
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 伊丹 貴晴

 

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