Pathophysiology of trauma-induced coagulopathy : disseminated intravascular coagulation with the fibrinolytic phenotype


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Title:	Pathophysiology of trauma-induced coagulopathy : disseminated intravascular coagulation with the fibrinolytic phenotype
Authors:	Hayakawa, Mineji Browse this author →KAKEN DB
Keywords:	Coagulopathy
	Disseminated intravascular coagulation
	Fibrinolysis
	Massive bleeding
	Transfusion
	Fibrinogen
	Trauma
Issue Date:	2017
Publisher:	BioMed Central
Journal Title:	Journal of Intensive Care
Volume:	5
Start Page:	14
Publisher DOI:	10.1186/s40560-016-0200-1
Abstract:	In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma. Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The pathophysiology of trauma-induced coagulopathy consists of coagulation activation, hyperfibrino(geno)lysis, and consumption coagulopathy. These pathophysiological mechanisms are the characteristics to DIC with the fibrinolytic phenotype.
Rights:	https://creativecommons.org/licenses/by/4.0/
Type:	article
URI:	http://hdl.handle.net/2115/66562
Appears in Collections:	医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 早川峰司

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