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Pathophysiology of trauma-induced coagulopathy : disseminated intravascular coagulation with the fibrinolytic phenotype

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Title: Pathophysiology of trauma-induced coagulopathy : disseminated intravascular coagulation with the fibrinolytic phenotype
Authors: Hayakawa, Mineji Browse this author →KAKEN DB
Keywords: Coagulopathy
Disseminated intravascular coagulation
Fibrinolysis
Massive bleeding
Transfusion
Fibrinogen
Trauma
Issue Date: 2017
Publisher: BioMed Central
Journal Title: Journal of Intensive Care
Volume: 5
Start Page: 14
Publisher DOI: 10.1186/s40560-016-0200-1
Abstract: In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma. Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The pathophysiology of trauma-induced coagulopathy consists of coagulation activation, hyperfibrino(geno)lysis, and consumption coagulopathy. These pathophysiological mechanisms are the characteristics to DIC with the fibrinolytic phenotype.
Rights: https://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/66562
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 早川 峰司

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