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Severe Methemoglobinemia due to Sodium Nitrite Poisoning

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Title: Severe Methemoglobinemia due to Sodium Nitrite Poisoning
Authors: Katabami, Kenichi Browse this author
Hayakawa, Mineji Browse this author →KAKEN DB
Gando, Satoshi Browse this author →KAKEN DB
Issue Date: 2016
Publisher: Hindawi
Journal Title: Case Reports in Emergency Medicine
Volume: 2016
Start Page: 9013816
Publisher DOI: 10.1155/2016/9013816
Abstract: Case. We report a case of severe methemoglobinemia due to sodium nitrite poisoning. A 28-year-old man was brought to our emergency department because of transient loss of consciousness and cyanosis. He was immediately intubated and ventilated with 100% oxygen. A blood test revealed a methemoglobin level of 92.5%. Outcome.We treated the patient with gastric lavage, activated charcoal, and methylene blue (2mg/kg) administered intravenously. Soon after receiving methylene blue, his cyanosis resolved and the methemoglobin level began to decrease. After relocation to the intensive care unit, his consciousness improved and he could recall ingesting approximately 15 g sodium nitrite about 1 hour before he was brought to our hospital.The patient was discharged on day 7 without neurologic impairment. Conclusion. Severe methemoglobinemia may be fatal. Therefore, accurate diagnosis of methemoglobinemia is very important so that treatment can be started as soon as possible.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 早川 峰司

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