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Genetic Diversity of Artybash Virus in the Laxmann's Shrew (Sorex caecutiens)
Title: | Genetic Diversity of Artybash Virus in the Laxmann's Shrew (Sorex caecutiens) |
Authors: | Arai, Satoru Browse this author | Kang, Hae Ji Browse this author | Gu, Se Hun Browse this author | Ohdachi, Satoshi D. Browse this author →KAKEN DB | Cook, Joseph A. Browse this author | Yashina, Liudmila N. Browse this author | Tanaka-Taya, Keiko Browse this author | Abramov, Sergey A. Browse this author | Morikawa, Shigeru Browse this author | Okabe, Nobuhiko Browse this author | Oishi, Kazunori Browse this author | Yanagihara, Richard Browse this author |
Keywords: | Hantavirus | RT-PCR | Shrew |
Issue Date: | 30-Jul-2016 |
Publisher: | Mary Ann Liebert, Inc. |
Journal Title: | Vector-Borne and Zoonotic Diseases |
Volume: | 16 |
Issue: | 7 |
Start Page: | 468 |
End Page: | 475 |
Publisher DOI: | 10.1089/vbz.2015.1903 |
Abstract: | Although based on very limited M and L segment sequences, Artybash virus (ARTV) was proposed previously as a unique hantavirus harbored by the Laxmann’s shrew (Sorex caecutiens). To verify this conjecture, lung tissues from 68 Laxmann’s shrews, captured during 2006 to 2014 in eastern Siberia, Russia, and Hokkaido, Japan, were analyzed for ARTV RNA using RT-PCR. ARTV RNA was detected in six Laxmann’s shrews. Pairwise alignment and comparison of partial- and full-length S, M, and L segment sequences from these Laxmann’s shrews, as well as phylogenetic analyses, using maximum likelihood and Bayesian methods indicated that ARTV was distinct from other soricine shrew-borne hantaviruses and representative hantaviruses harbored by rodents, moles, and bats. Taxonomic identity of the ARTV-infected Laxmann’s shrews was confirmed by full-length cytochrome b mitochondrial DNA sequence analysis. Our data indicate that the hantavirus previously known as Amga virus (MGAV) represents genetic variants of ARTV. Thus, the previously proposed designation of ARTV/MGAV should be replaced by ARTV |
Rights: | Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/vbz.2015.1903 |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/66902 |
Appears in Collections: | 低温科学研究所 (Institute of Low Temperature Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 大舘 智志
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