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Freezing preparation for macroscopic forensic investigation in putrefied brain

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Title: Freezing preparation for macroscopic forensic investigation in putrefied brain
Authors: Matoba, Kotaro Browse this author →KAKEN DB
Hyodoh, Hideki Browse this author →KAKEN DB
Murakami, Manabu Browse this author
Matoba, Tomoko Browse this author
Saito, Atsuko Browse this author
Feng, Fei Browse this author
Jin, Shigeki Browse this author →KAKEN DB
Keywords: Postmortem CT: freeze
Putrefaction
Brain
Forensic pathology
Issue Date: May-2017
Publisher: Elsevier
Journal Title: Legal medicine
Volume: 26
Start Page: 6
End Page: 10
Publisher DOI: 10.1016/j.legalmed.2017.01.005
PMID: 28549549
Abstract: Purpose: To evaluate the usefulness of the applied freezing technique in putrefied brain for macroscopic investigation. Materials and methods: From October 2015 to September 2016, first the brains of 10 cadavers (control group: male 6, female 4, age 20-80 (mean 61.5), postmortem intervals (PMI) 14-75 (mean 29.7) days) were inspected following the standard practice (without freezing preparation), and then with 10 cadavers (freezing group: male 7, female 3, age 41-88 (mean 60.4), PMI 7-75 (mean 29.2) days) the freezing technique was used before the autopsy. The cut brain was investigated, and the gray-white matter difference was evaluated macroscopically. Results: In the control group, the brain parenchyma leaked out like sludge in 5, and there was difficulty maintaining its structure in 7. The gray-white matter difference was well visible in 3, but hard to distinguish in 3, and the total scores ranged from 0 to 9 (mean 4.4) points. In the freezing group, the entire putrefied brain was extracted as a solid organ, the gray-white matter differences were well visible, and the total scores were 6.7-9 (8.3) points. The gray-white matter difference was preserved in the freezing group (p < 0.05). Conclusion: The freezing procedures to evaluate the putrefied brain have been successfully applied, and it could be statistically more useful in putrefied brain investigation than the ordinary procedure. Postmortem CT can be useful to evaluate not only the degree of brain putrefaction, but also the degree of brain parenchyma freezing.
Rights: http://creativecommons.org/licenses/by-nc-nd/4.0/
Type: article
URI: http://hdl.handle.net/2115/66990
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 兵頭 秀樹

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