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Association between suicide-related ideations and affective temperaments in the Japanese general adult population

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Title: Association between suicide-related ideations and affective temperaments in the Japanese general adult population
Authors: Mitsui, Nobuyuki Browse this author
Nakai, Yukiei Browse this author
Inoue, Takeshi Browse this author →KAKEN DB
Udo, Niki Browse this author
Kitagawa, Kan Browse this author
Wakatsuki, Yumi Browse this author
Kameyama, Rie Browse this author
Toyomaki, Atsuhito Browse this author →KAKEN DB
Ito, Yoichi M. Browse this author →KAKEN DB
Kitaichi, Yuji Browse this author →KAKEN DB
Nakagawa, Shin Browse this author →KAKEN DB
Kusumi, Ichiro Browse this author →KAKEN DB
Issue Date: 22-Jun-2017
Publisher: The Public Library of Science
Journal Title: PLoS ONE
Volume: 12
Issue: 6
Start Page: e0179952
Publisher DOI: 10.1371/journal.pone.0179952
Abstract: Background: Suicide rates are vastly higher in Japan than in many other countries, although the associations between affective temperaments and suicide-related ideations in the general adult population remain unclear. Therefore, we aimed to elucidate these associations in the present study. Methods: We analyzed data from 638 Japanese volunteers who completed both the Patient Health Questionnaire (PHQ-9) and the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Auto-questionnaire (TEMPS-A). Participants were then divided into three groups based on PHQ-9 summary scores and responses to the suicide-related ideation item: non-depressive control group (NC; N = 469), depressive symptoms without suicide-related ideations group (non-SI; N = 135), and depressive symptoms with suicide-related ideations group (SI; N = 34). The depressive symptoms were defined for PHQ-9 summary scores ≥5, and the suicide-related ideations were defined for PHQ-9 #9 score ≥1. We then compared TEMPS-A scores among the groups using Kruskal-Wallis tests. Then the 95% confidence intervals of differences in TEMPS-A subscale scores between the NC and non-SI groups, or between NC and SI groups, were calculated. Results: Participants of the SI group exhibited significantly higher scores on the depressive, irritable, and anxious temperament subscales than those of the non-SI group. Similarly, women of the SI group exhibited significantly higher scores of the depressive and irritable temperament subscales than women of the non-SI group, while men of the SI group exhibited significantly higher depressive temperament scores than those of the non-SI group. Among all participants and only men, cyclothymic subscale scores were higher in those of the SI group than the non-SI group (not significant), although the 95% confidence intervals did not overlap. Limitations: The cross-sectional study design was the main limitation. Conclusions: Depressive, irritable, and anxious temperaments are significant risk factors for suicide-related ideations in the Japanese general adult population. Furthermore, irritable temperament in women and depressive temperament in men are associated with suicide-related ideations.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 三井 信幸

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