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Time-related change evaluation of the cerebrospinal fluid using postmortem CT

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Title: Time-related change evaluation of the cerebrospinal fluid using postmortem CT
Authors: Morikawa, Kohei Browse this author
Hyodoh, Hideki Browse this author →KAKEN DB
Matoba, Kotaro Browse this author →KAKEN DB
Mizuo, Keisuke Browse this author →KAKEN DB
Okazaki, Shunichiro Browse this author
Watanabe, Satoshi Browse this author
Keywords: Postmortem CT
Cerebrospinal fluid
Postmortem interval
Postmortem change
Forensic radiology
Issue Date: Sep-2016
Publisher: Elsevier
Journal Title: Legal medicine
Volume: 22
Start Page: 30
End Page: 35
Publisher DOI: 10.1016/j.legalmed.2016.07.010
PMID: 27591536
Abstract: Purpose: We retrospectively evaluated the cerebro-spinal fluid (CSF) CT density at the lateral ventricle to compare the postmortem intervals in cadavers. Materials and methods: The number of cadavers enrolled in this study was 189 (male 120, female 69). According to the estimated postmortem time, the cadavers were divided into 13 groups (postmortem day 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 7, 10, 14, 21, 30), and were also re-grouped into 3 groups according to the postmortem time-width: group A (postmortem day 0.5-2.5), group B (day 3-7), and group C (day 10-30). Comparisons between the CSF density and estimated postmortem time were also analyzed. Results: The CSF density was around 20 HU up to day 2.5, and it increased gradually after day 3. Day 3 and 4 presented higher CSF density than day 1 and 1.5 (p < 0.05). Day 7 presented higher CSF density than day 3 (p < 0.05). According to the postmortem time-width, the CSF density increased with postmortem time (p < 0.05). The simple linear regression equations presented negative correlation between CSF density and estimated postmortem time, and R2 was 0.119. Conclusion: The CSF density increased, but not linearly, according to the postmortem time, and the 3rd postmortem day was the earliest time allowing the difference to be detected. The CSF density needs further evaluation to enable estimation of the postmortem time.
Rights: © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
http://creativecommons.org/licenses/by-nc-nd/4.0/
Type: article (author version)
URI: http://hdl.handle.net/2115/67077
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 兵頭 秀樹

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