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Variation in the coat-color-controlling genes, Mc1r and Asip,in the house mouse Mus musculus from Madagascar

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タイトル: Variation in the coat-color-controlling genes, Mc1r and Asip,in the house mouse Mus musculus from Madagascar
著者: Sakuma, Yuki 著作を一覧する
Ranorosoa, Marie C. 著作を一覧する
Kinoshita, Gohta 著作を一覧する
Shimoji, Hiroyuki 著作を一覧する
Tsuchiya, Kimiyuki 著作を一覧する
Ohdachi, Satoshi D. 著作を一覧する
Arai, Satoru 著作を一覧する
Tanaka, Chihiro 著作を一覧する
Ramino, Hajanirina 著作を一覧する
Suzuki, Hitoshi 著作を一覧する
発行日: 2016年 9月 1日
出版者: The Mammal Society of Japan
誌名: Mammal Study
巻: 41
号: 3
開始ページ: 131
終了ページ: 140
出版社 DOI: 10.3106/041.041.0303
抄録: Variability in the coat color of the house mouse, Mus musculus, provides an opportunity to study the evolution of phenotypes in this species. Here we associated genetic variations with coat color in seven mice from Madagascar that had identical M. m. gentilulus mitochondrial DNA sequences. The entire coding region of the 948-base pair (bp) coat-color-related gene, Mc1r, was shown to have no nonsynonymous changes. However, analyses of the two exon-1 promoter regions—termed 1A (317 bp) and 1B (499 bp)—from a second gene, Asip, which is also involved in the evolution of coat color, revealed two distinct haplotypes in each region. Associations between Asip promoter regions and dorsal color were ambiguous; however, two ventral color types—light and dark gray—were associated with the haplotypes of 1A, as determined by clustering analysis. Notably, the haplotype of the light gray animals was identical to the Asip Aw allele that is associated with white bellies.
資料タイプ: article
URI: http://hdl.handle.net/2115/67092
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 大舘 智志

 

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