|
|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Association of impaired renal function and poor prognosis in oropharyngeal squamous cell carcinoma
| Title: | Association of impaired renal function and poor prognosis in oropharyngeal squamous cell carcinoma |
| Other Titles: | Renal function and oropharyngeal cancer |
| Authors: | Homma, Akihiro Browse this author →KAKEN DB | | Hayashi, Ryuichi Browse this author | | Kawabata, Kazuyoshi Browse this author | | Fujii, Takashi Browse this author | | Iwae, Shigemichi Browse this author | | Hasegawa, Yasuhisa Browse this author →KAKEN DB | | Nibu, Kenichi Browse this author | | Kato, Takakuni Browse this author →KAKEN DB | | Shiga, Kiyoto Browse this author →KAKEN DB | | Matsuura, Kazuto Browse this author →KAKEN DB | | Monden, Nobuya Browse this author | | Fujii, Masato Browse this author →KAKEN DB |
| Keywords: | oropharyngeal cancer | | squamous cell carcinoma | | prognosis | | renal function | | comorbidity |
| Issue Date: | Oct-2016 |
| Publisher: | Wiley |
| Journal Title: | Head & neck |
| Volume: | 38 |
| Issue: | 10 |
| Start Page: | 1495 |
| End Page: | 1500 |
| Publisher DOI: | 10.1002/hed.24467 |
| PMID: | 27044005 |
| Abstract: | BACKGROUND: Renal function influences decisions regarding treatment for patients with squamous cell carcinoma of the oropharynx (SCC-OP). However, the importance of renal function in SCC-OP has not yet been reported. METHODS: Four hundred and sixty patients with SCC-OP treated with curative intent between April 2005 and March 2007 in 12 institutions in Japan were analyzed retrospectively. RESULTS: Four hundred and three patients (87.6%) showed a Ccr ≥50 mL/min and 57 (12.4%) a Ccr <50 mL/min. Age was associated with worse overall survival (OS), while stage IVB, radiotherapy, and Ccr<50 were associated with worse OS on univariate analyses. Surgery and hypertension were associated with better OS on univariate analyses. On multivariate analysis, age, stage, hypertension, and Ccr were also found to be significantly associated with OS. CONCLUSIONS: Based on this retrospective study, impaired renal function is an independent predictor of increased risk of death in patients with SCC-OP. |
| Rights: | This is the peer reviewed version of the following article: Homma, A., Hayashi, R., Kawabata, K., Fujii, T., Iwae, S., Hasegawa, Y., Nibu, K., Kato, T., Shiga, K., Matsuura, K., Monden, N. and Fujii, M. (2016), Association of impaired renal function and poor prognosis in oropharyngeal squamous cell carcinoma. Head Neck, 38: 1495–1500, which has been published in final form at http://dx.doi.org/10.1002/hed.24467. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/67223 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 本間 明宏
|
