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A comparison between fentanyl plus celecoxib therapy and epidural anesthesia for postoperative pain management following laparoscopic gastrectomy

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Title: A comparison between fentanyl plus celecoxib therapy and epidural anesthesia for postoperative pain management following laparoscopic gastrectomy
Other Titles: Pain control by fentanyl and celecoxib
Authors: Shibasaki, Susumu Browse this author
Kawamura, Hideki Browse this author →KAKEN DB
Homma, Shigenori Browse this author →KAKEN DB
Yosida, Tadashi Browse this author
Takahashi, Shusaku Browse this author
Takahashi, Masahiro Browse this author
Takahashi, Norihiko Browse this author
Taketomi, Akinobu Browse this author →KAKEN DB
Keywords: Laparoscopic gastrectomy
Postoperative pain
Epidural anesthesia
Celecoxib
Fentanyl
Issue Date: Oct-2016
Publisher: Springer
Journal Title: Surgery today
Volume: 46
Issue: 10
Start Page: 1209
End Page: 1216
Publisher DOI: 10.1007/s00595-015-1290-4
PMID: 26695406
Abstract: Purpose: To clarify the efficacy of postoperative pain management following laparoscopic gastrectomy (LG), we retrospectively compared pain assessments in patients who received fentanyl plus celecoxib with those who received epidural anesthesia. Methods: From 2011 to 2012, 55 consecutive LG patients at our institution received 48 h of epidural anesthesia for postoperative pain management (group-E). Since September 2013, epidural anesthesia was replaced with 24 h of intravenous fentanyl and 4 days of oral celecoxib. Thirty-three consecutive LG patients who received this analgesic method (group-FC) were included in this analysis. The severity of postoperative pain as assessed by the FACES Pain Rating Scale and the frequency of rescue pain medication were retrospectively compared between the two groups. Results: No significant difference in the severity of postoperative pain on postoperative day (POD) 0 or 1 was observed between the two groups. In contrast, pain was significantly lower in group-FC than group-E on PODs 2, 3, 4, and 7. The total use of rescue pain medications during the first 7 days following LG did not differ between the two groups. Conclusion: Pain management using 24 h of intravenous fentanyl and 4 days of oral celecoxib is comparable to epidural anesthesia following LG.
Rights: The final publication is available at Springer via http://dx.doi.org/10.1007/s00595-015-1290-4
Type: article (author version)
URI: http://hdl.handle.net/2115/67231
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 川村 秀樹

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