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Characteristic systolic waveform of left ventricular longitudinal strain rate in patients with hypertrophic cardiomyopathy

Heart Vessels 2016 Oct 18.pdf1.07 MBPDF見る/開く

タイトル: Characteristic systolic waveform of left ventricular longitudinal strain rate in patients with hypertrophic cardiomyopathy
著者: Okada, Kazunori 著作を一覧する
Kaga, Sanae 著作を一覧する
Mikami, Taisei 著作を一覧する
Masauzi, Nobuo 著作を一覧する
Abe, Ayumu 著作を一覧する
Nakabachi, Masahiro 著作を一覧する
Yokoyama, Shinobu 著作を一覧する
Nishino, Hisao 著作を一覧する
Ichikawa, Ayako 著作を一覧する
Nishida, Mutsumi 著作を一覧する
Murai, Daisuke 著作を一覧する
Hayashi, Taichi 著作を一覧する
Shimizu, Chikara 著作を一覧する
Iwano, Hiroyuki 著作を一覧する
Yamada, Satoshi 著作を一覧する
Tsutsui, Hiroyuki 著作を一覧する
キーワード: Hypertension
Hypertrophic cardiomyopathy
Speckle tracking echocardiography
Strain-rate waveform
発行日: 2016年10月18日
出版者: Springer
誌名: Heart and Vessels
巻: 32
号: 5
開始ページ: 591
終了ページ: 599
出版社 DOI: 10.1007/s00380-016-0906-y
抄録: We analyzed the waveform of systolic strain and strain-rate curves to find a characteristic left ventricular (LV) myocardial contraction pattern in patients with hypertrophic cardiomyopathy (HCM), and evaluated the utility of these parameters for the differentiation of HCM and LV hypertrophy secondary to hypertension (HT). From global strain and strain-rate curves in the longitudinal and circumferential directions, the time from mitral valve closure to the peak strains (T-LS and T-CS, respectively) and the peak systolic strain rates (T-LSSR and T-CSSR, respectively) were measured in 34 patients with HCM, 30 patients with HT, and 25 control subjects. The systolic strain-rate waveform was classified into 3 patterns ("V", "W", and "√" pattern). In the HCM group, T-LS was prolonged, but T-LSSR was shortened; consequently, T-LSSR/T-LS ratio was distinctly lower than in the HT and control groups. The "√" pattern of longitudinal strain-rate waveform was more frequently seen in the HCM group (74 %) than in the control (4 %) and HT (20 %) groups. Similar but less distinct results were obtained in the circumferential direction. To differentiate HCM from HT, the sensitivity and specificity of the T-LSSR/T-LS ratio <0.34 and the "√"-shaped longitudinal strain-rate waveform were 85 and 63 %, and 74 and 80 %, respectively. In conclusion, in patients with HCM, a reduced T-LSSR/T-LS ratio and a characteristic "√"-shaped waveform of LV systolic strain rate was seen, especially in the longitudinal direction. The timing and waveform analyses of systolic strain rate may be useful to distinguish between HCM and HT.
Rights: The final publication is available at Springer via
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 岡田 一範


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