Title: | Characteristic systolic waveform of left ventricular longitudinal strain rate in patients with hypertrophic cardiomyopathy |
Authors: | Okada, Kazunori Browse this author |
Kaga, Sanae Browse this author |
Mikami, Taisei Browse this author →KAKEN DB |
Masauzi, Nobuo Browse this author |
Abe, Ayumu Browse this author |
Nakabachi, Masahiro Browse this author |
Yokoyama, Shinobu Browse this author |
Nishino, Hisao Browse this author |
Ichikawa, Ayako Browse this author |
Nishida, Mutsumi Browse this author →KAKEN DB |
Murai, Daisuke Browse this author |
Hayashi, Taichi Browse this author |
Shimizu, Chikara Browse this author →KAKEN DB |
Iwano, Hiroyuki Browse this author |
Yamada, Satoshi Browse this author →KAKEN DB |
Tsutsui, Hiroyuki Browse this author →KAKEN DB |
Keywords: | Hypertension |
Hypertrophic cardiomyopathy |
Speckle tracking echocardiography |
Strain-rate waveform |
Issue Date: | 18-Oct-2016 |
Publisher: | Springer |
Journal Title: | Heart and Vessels |
Volume: | 32 |
Issue: | 5 |
Start Page: | 591 |
End Page: | 599 |
Publisher DOI: | 10.1007/s00380-016-0906-y |
PMID: | 27757525 |
Abstract: | We analyzed the waveform of systolic strain and strain-rate curves to find a characteristic left ventricular (LV) myocardial contraction pattern in patients with hypertrophic cardiomyopathy (HCM), and evaluated the utility of these parameters for the differentiation of HCM and LV hypertrophy secondary to hypertension (HT). From global strain and strain-rate curves in the longitudinal and circumferential directions, the time from mitral valve closure to the peak strains (T-LS and T-CS, respectively) and the peak systolic strain rates (T-LSSR and T-CSSR, respectively) were measured in 34 patients with HCM, 30 patients with HT, and 25 control subjects. The systolic strain-rate waveform was classified into 3 patterns ("V", "W", and "√" pattern). In the HCM group, T-LS was prolonged, but T-LSSR was shortened; consequently, T-LSSR/T-LS ratio was distinctly lower than in the HT and control groups. The "√" pattern of longitudinal strain-rate waveform was more frequently seen in the HCM group (74 %) than in the control (4 %) and HT (20 %) groups. Similar but less distinct results were obtained in the circumferential direction. To differentiate HCM from HT, the sensitivity and specificity of the T-LSSR/T-LS ratio <0.34 and the "√"-shaped longitudinal strain-rate waveform were 85 and 63 %, and 74 and 80 %, respectively. In conclusion, in patients with HCM, a reduced T-LSSR/T-LS ratio and a characteristic "√"-shaped waveform of LV systolic strain rate was seen, especially in the longitudinal direction. The timing and waveform analyses of systolic strain rate may be useful to distinguish between HCM and HT. |
Rights: | The final publication is available at Springer via http://dx.doi.org/10.1007/s00380-016-0906-y. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/67323 |
Appears in Collections: | 保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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