|
Hokkaido University Collection of Scholarly and Academic Papers >
Societies >
北海道歯学雑誌 >
第38巻 記念特集号 >
Characteristics and properties of gingival mesenchymal stem cells
| Title: | Characteristics and properties of gingival mesenchymal stem cells |
| Authors: | Iizuka, Tadashi Browse this author | | Takahashi, Tomomi Browse this author | | Ushijima, Natsumi Browse this author |
| Keywords: | mesenchymal stem cell | | gingiva | | regeneration | | multilineage differentiation |
| Issue Date: | Sep-2017 |
| Publisher: | 北海道歯学会 |
| Journal Title: | 北海道歯学雑誌 |
| Volume: | 38 |
| Issue: | Special issue |
| Start Page: | 40 |
| End Page: | 46 |
| Abstract: | The gingiva is a unique oral tissue overlaying the alveolar ridges. It is recognized as a biological mucosal barrier and a distinct component of the oral mucosal immunity. This tissue can easily be obtained in the clinic as a discarded biological sample. Recently, gingival mesenchymal stem cells (G-MSCs) have been isolated and characterized as abundant and easily accessible, as compared to other mesenchymal stem cell sources. Many reports described G-MSCs as having much potential for multilineage differentiation and show remarkable tissue regenerative properties. Primary experimental therapeutic applications of G-MSCs are potentially superior to conventional clinical treatment modalities. Several studies have recently applied G-MSCs to stem cell-based therapy and revealed that G-MSCs have many advantages as a candidate cell source for bone regeneration and periodontal tissue regeneration. This review summarizes the scientific evidence on G-MSCs' isolation, their characterization, and their regenerative properties. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/67335 |
| Appears in Collections: | 北海道歯学雑誌 > 第38巻 記念特集号
|
|
