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Hokkaido University Collection of Scholarly and Academic Papers >
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北海道歯学雑誌 >
第38巻 記念特集号 >
Vascular formation : in vitro differentiation of vascular endothelial cells from pluripotent stem cells
| Title: | Vascular formation : in vitro differentiation of vascular endothelial cells from pluripotent stem cells |
| Authors: | Tsuji-Tamura, Kiyomi Browse this author | | Tamura, Masato Browse this author →KAKEN DB | | Tsuji-Tamura Browse this author |
| Keywords: | vascular formation | | vascular endothelial cells | | VEGF | | ES cells |
| Issue Date: | Sep-2017 |
| Publisher: | 北海道歯学会 |
| Journal Title: | 北海道歯学雑誌 |
| Volume: | 38 |
| Issue: | Special issue |
| Start Page: | 80 |
| End Page: | 85 |
| Abstract: | During early vascular development, vascular endothelial cells (ECs) differentiate, proliferate, migrate, and change morphologically, forming tube-like vascular structures. The ECs are then surrounded by vascular smooth muscle cells (SMCs), leading to the formation of stable vascular structures, or vascular maturation. The stages of cell or tissue development can be monitored and analyzed using in vitro differentiation systems of pluripotent stem cells. In this review, we present the molecular mechanisms that regulate the developmental processes of vasculature. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/67345 |
| Appears in Collections: | 北海道歯学雑誌 > 第38巻 記念特集号
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