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Vascular formation : in vitro differentiation of vascular endothelial cells from pluripotent stem cells

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Title: Vascular formation : in vitro differentiation of vascular endothelial cells from pluripotent stem cells
Authors: Tsuji-Tamura, Kiyomi Browse this author
Tamura, Masato Browse this author →KAKEN DB
Tsuji-Tamura Browse this author
Keywords: vascular formation
vascular endothelial cells
VEGF
ES cells
Issue Date: Sep-2017
Publisher: 北海道歯学会
Journal Title: 北海道歯学雑誌
Volume: 38
Issue: Special issue
Start Page: 80
End Page: 85
Abstract: During early vascular development, vascular endothelial cells (ECs) differentiate, proliferate, migrate, and change morphologically, forming tube-like vascular structures. The ECs are then surrounded by vascular smooth muscle cells (SMCs), leading to the formation of stable vascular structures, or vascular maturation. The stages of cell or tissue development can be monitored and analyzed using in vitro differentiation systems of pluripotent stem cells. In this review, we present the molecular mechanisms that regulate the developmental processes of vasculature.
Type: article
URI: http://hdl.handle.net/2115/67345
Appears in Collections:北海道歯学雑誌 = Hokkaido Journal of Dental Science > 第38巻 記念特集号

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