| Title: | Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros) |
| Authors: | Carr, Michael Browse this author |
| Kawaguchi, Akira Browse this author |
| Sasaki, Michihito Browse this author →KAKEN DB |
| Gonzalez, Gabriel Browse this author |
| Ito, Kimihito Browse this author →KAKEN DB |
| Thomas, Yuka Browse this author |
| Hang'ombe, Bernard M. Browse this author |
| Mweene, Aaron S. Browse this author |
| Zhao, Guoyan Browse this author |
| Wang, David Browse this author |
| Orba, Yasuko Browse this author →KAKEN DB |
| Ishii, Akihiro Browse this author →KAKEN DB |
| Sawa, Hirofumi Browse this author →KAKEN DB |
| Keywords: | Simian immunodeficiency virus |
| SIV |
| African green monkey |
| Zambia |
| Chlorocebus cynosuros |
| malbrouck |
| next generation sequencing |
| virus discovery |
| Issue Date: | 1-Nov-2016 |
| Publisher: | Springer |
| Journal Title: | Archives of virology |
| Volume: | 162 |
| Issue: | 2 |
| Start Page: | 543 |
| End Page: | 548 |
| Publisher DOI: | 10.1007/s00705-016-3129-8 |
| PMID: | 27804019 |
| Abstract: | To investigate the diversity of simian immunodeficiency virus (SIV) among nonhuman primates (NHPs) in Zambia, next-generation sequencing was performed to determine the complete genome sequence of a novel SIV recovered by co-culturing African green monkey (AGM) peripheral blood lymphocytes with human CD4(+) T-cell lines. We report the first described SIV (SIVagmMAL-ZMB) from a malbrouck (Chlorocebus cynosuros). SIVagmMAL-ZMB was detected by real-time PCR analysis of splenic RNA in 3.2% (3/94) of AGMs and was undetectable in baboons (0/105). SIVagmMAL-ZMB possessed < 80% nucleotide sequence identity to known SIV isolates and was located basally to vervet monkey SIV strains in all phylogenies. |
| Rights: | The final publication is available at Springer via http://dx.doi.org/10.1007/s00128-016-2011-4 |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/67556 |
| Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
