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Health-related quality of life in patients with spinal dural arteriovenous fistulae

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Title: Health-related quality of life in patients with spinal dural arteriovenous fistulae
Authors: Sasamori, Toru Browse this author →KAKEN DB
Hida, Kazutoshi Browse this author →KAKEN DB
Osanai, Toshiya Browse this author →KAKEN DB
Yano, Shunsuke Browse this author
Seki, Toshitaka Browse this author
Houkin, Kiyohiro Browse this author →KAKEN DB
Keywords: Health-related quality of life (HRQOL)
Patient-reported outcome (PRO)
Spinal dural arteriovenous fistulae (SDAVF)
Short-form 36 Health Survey (SF-36)
Issue Date: Jan-2017
Publisher: Springer
Journal Title: Neurosurgical review
Volume: 40
Issue: 1
Start Page: 83
End Page: 86
Publisher DOI: 10.1007/s10143-016-0752-5
PMID: 27194130
Abstract: Background: Neurological improvement in patients with spinal dural arteriovenous fistulae (SDAVF) is often partial even after adequate treatment. While treatment outcomes have been evaluated primarily on the basis of the postoperative changes in neurological deficits, outcome measures should also reflect the patient-reported outcome (PRO). Methods: We conducted a health-related quality of life (HRQOL) survey in 52 SDAVF patients; 33 (63.5%) completed the short-form 36 Health Survey (SF-36) questionnaire. They were 25 males and 8 females ranging in age from 47 to 85 years (mean age 70.0 years). The mean follow-up period was 95.6 months. We analyzed the completed questionnaires and examined the clinical factors associated with their HRQOL. Results: After treatment, gait- and micturition disturbances persisted in 31 (93.9%) and 31 (93.9%) of our patients; 26 (78.8%) reported chronic leg pain. The SF-36 scores of treated SDAVF patients were significantly lower than the national average of 50 for all 8 sub-items in the questionnaire. The scores for physical functioning (PF) and role-physical (RP) were particularly low. With the exception of bodily pain (BP), there was a significant negative correlation between the Aminoff-Logue scale (ALS) scores for gait and micturition and the sub-item scores. The score for BP showed a significant positive correlation with the scores for the 7 other SF-36 sub-items. Conclusions: The HRQOL of treated SDAVF patients was lower than the national average with respect to both physical and mental aspects. Persistent post-treatment pain and gaitand micturition disturbances were responsible for their lower HRQOL.
Rights: The final publication is available at Springer via
Type: article (author version)
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 笹森 徹

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