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A new method to estimate pulmonary vascular resistance using diastolic pulmonary artery-right ventricular pressure gradients derived from continuous-wave Doppler velocity measurements of pulmonary regurgitation

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この文献へのリンクには次のURLを使用してください:http://hdl.handle.net/2115/68252

タイトル: A new method to estimate pulmonary vascular resistance using diastolic pulmonary artery-right ventricular pressure gradients derived from continuous-wave Doppler velocity measurements of pulmonary regurgitation
著者: Kaga, Sanae 著作を一覧する
Mikami, Taisei 著作を一覧する
Murayama, Michito 著作を一覧する
Okada, Kazunori 著作を一覧する
Masauzi, Nobuo 著作を一覧する
Nakabachi, Masahiro 著作を一覧する
Nishino, Hisao 著作を一覧する
Yokoyama, Shinobu 著作を一覧する
Nishida, Mutsumi 著作を一覧する
Hayashi, Taichi 著作を一覧する
Murai, Daisuke 著作を一覧する
Iwano, Hiroyuki 著作を一覧する
Sakakibara, Mamoru 著作を一覧する
Yamada, Satoshi 著作を一覧する
Tsutsui, Hiroyuki 著作を一覧する
キーワード: Pulmonary vascular resistance
Echocardiography
Pulmonary regurgitation
Left heart failure
発行日: 2017年 1月
出版者: Springer
誌名: International journal of cardiovascular imaging
巻: 33
号: 1
開始ページ: 31
終了ページ: 38
出版社 DOI: 10.1007/s10554-016-0965-2
抄録: Pulmonary vascular resistance (PVR) is an important hemodynamic parameter in patients with heart failure, especially when the pulmonary arterial pressure is lower due to reduced stroke volume. Several echocardiographic methods to estimate PVR have been proposed, but their applications in patients with organic left-sided heart diseases have been limited. The aim of the present study was to examine the usefulness of our new method to estimate PVR (PVRPR) based on the continuous-wave Doppler velocity measurements of pulmonary regurgitation in these patients. In 43 patients who underwent right heart catheterization, PVRPR was calculated as the difference between the Doppler-derived early- and end-diastolic pulmonary artery (PA)-right ventricular (RV) pressure gradients divided by the cardiac output measured in the left ventricular outflow tract by echocardiography. The PVRPR correlated well with invasive PVR (PVRCATH) (r = 0.81, p < 0.001) without any fixed bias in Bland-Altman analysis. The conventional echocardiographic PVRs showed inadequate correlations with PVRCATH, or a obvious overestimation of PVRCATH. In the receiver operating characteristic analyses to determine the patients with abnormal elevation of PVRCATH (> 3 Wood units, WU), the area under the curve was the greatest for PVRPR (0.964) compared to the conventional PVRs (0.649-0.839). PVRPR had 83 % sensitivity and 100 % specificity at the optimal cut-off value of 3.10 WU in identifying patients with PVRCATH > 3 WU. Our simple and theoretical PVRPR is useful for the noninvasive estimation of PVR.
Rights: This is a post-peer-review, pre-copyedit version of an article published in International journal of cardiovascular imaging. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10554-016-0965-2
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/68252
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 加賀 早苗

 

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