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Echocardiography findings in a case with Ballantyne syndrome

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Title: Echocardiography findings in a case with Ballantyne syndrome
Authors: Suzuki, Yutaro Browse this author
Yamamura, Mie Browse this author
Kikuchi, Keisuke Browse this author
Hattori, Rifumi Browse this author
Umazume, Takeshi Browse this author →KAKEN DB
Minakami, Hisanori Browse this author →KAKEN DB
Keywords: heart failure
renin-angiotensin-aldosterone system (RAAS)
soluble fms-like tyrosine kinase-1 (sFlt-1)
triple edema syndrome
Issue Date: Feb-2017
Publisher: John Wiley & Sons
Journal Title: Journal of Obstetrics and Gynaecology Research
Volume: 43
Issue: 2
Start Page: 387
End Page: 391
Publisher DOI: 10.1111/jog.13209
PMID: 27987334
Abstract: Marked fluid retention occurs in Ballantyne syndrome, but few reports are available on changes in cardiac morphology in this syndrome. A woman with generalized edema, dyspnea, fetal hydrops (skin edema and ascites), thickened placenta, and elevated plasma B-type natriuretic peptide level (344 pg/mL) was admitted to our hospital at gestational week (GW) 20^+3. Blood pressure remained within the normal range. However, acute increases in left atrial volume index, pulmonary artery systolic pressure, and hyperdynamic left ventricular function (as evidenced by increased left ventricular ejection fraction to 74% with cardiac index of 5.1 L/min/m2) occurred preceding fetal death at GW 21^+4 in the presence of increased inferior vena cava diameter (23 mm) and relatively low systemic vascular resistance of 752 dyn・s/cm5. These findings suggested life-threatening heart failure and required cesarean delivery at GW 21^+5 resulting in complete recovery. The placenta suggested cytomegalovirus infection.
Rights: This is the peer reviewed version of the following article: Suzuki, Y., Yamamura, M., Kikuchi, K., Hattori, R., Umazume, T., and Minakami, H. (2017) Echocardiography findings in a case with Ballantyne syndrome. J. Obstet. Gynaecol. Res., 43: 387–391, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 水上 尚典

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