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Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection
Title: | Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection |
Authors: | Yoshida, Tadashi Browse this author →KAKEN DB | Homma, Shigenori Browse this author →KAKEN DB | Shibasaki, Susumu Browse this author | Shimokuni, Tatsushi Browse this author | Sakihama, Hideyasu Browse this author →KAKEN DB | Takahashi, Norihiko Browse this author | Kawamura, Hideki Browse this author →KAKEN DB | Taketomi, Akinobu Browse this author →KAKEN DB |
Keywords: | Anesthesia | Laparoscopy | Colon |
Issue Date: | Feb-2017 |
Publisher: | Springer |
Journal Title: | Surgery today |
Volume: | 47 |
Issue: | 2 |
Start Page: | 174 |
End Page: | 181 |
Publisher DOI: | 10.1007/s00595-016-1356-y |
PMID: | 27194126 |
Abstract: | Purpose: Effective postoperative analgesia is essential to a patient’s recovery after laparoscopic colon resection (LCR). We introduce a new analgesic protocol using fentanyl plus celecoxib following LCR. Methods: The subjects of this retrospective comparative study were 137 patients who underwent LCR, 63 of whom were treated with 72 h of epidural anesthesia (group E), and 74 of whom were treated with 24 h of fentanyl intravenous injection followed by 7 days of oral celecoxib (group FC). We evaluated the safety and efficacy of this new protocol. Results: The combination of fentanyl and celecoxib maintained a low postoperative pain score (<1.5, evaluated by the FACES Pain Scale) and reduced the need for rescue analgesic drugs for 7 days (groups E vs. FC: 5.39 ± 3.77 vs. 2.79 ± 2.92, p < 0.001). The postoperative hospital stay was almost equal for the two groups (E vs. FC: 11.1 ± 4.5 vs. 10.3 ± 4.8 days, p = 0.315). The operating room stay other than for surgery was significantly shorter for group FC (E vs. FC: 128.7 ± 30.5 vs. 107.2 ± 17.0 min, p < 0.001). Neither group experienced complications, apart from one group FC patient, who suffered transient nausea and vertigo. Conclusions: The new analgesic protocol using fentanyl plus celecoxib is an effective and time-saving strategy for LCR. |
Rights: | The final publication is available at Springer via http://dx.doi.org/10.1007/s00595-016-1356-y |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/68259 |
Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 吉田 雅
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