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Impact of elemental diet on early recovery after laparoscopic colectomy : findings of a randomized controlled trial

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Title: Impact of elemental diet on early recovery after laparoscopic colectomy : findings of a randomized controlled trial
Other Titles: Elemental Diet in Lap Colon
Authors: Shichinohe, Toshiaki Browse this author →KAKEN DB
Sasaki, Takeshi Browse this author
Kitashiro, Shuji Browse this author
Morita, Takayuki Browse this author
Ono, Koichi Browse this author
Senmaru, Naoto Browse this author
Ikeda, Junichi Browse this author
Kojima, Tetsufumi Browse this author
Kyogoku, Noriaki Browse this author
Yamada, Hidehisa Browse this author
Sato, Nagato Browse this author
Kato, Kentaro Browse this author →KAKEN DB
Murakami, Soichi Browse this author
Ebihara, Yuma Browse this author →KAKEN DB
Kurashima, Yo Browse this author →KAKEN DB
Tamoto, Eiji Browse this author
Noji, Takehiro Browse this author →KAKEN DB
Nakamura, Toru Browse this author →KAKEN DB
Okamura, Keisuke Browse this author
Tsuchikawa, Takahiro Browse this author →KAKEN DB
Hirano, Satoshi Browse this author →KAKEN DB
Keywords: elemental diet
laparoscopic colectomy
estimated minimum length of stay in hospital
Issue Date: Feb-2017
Publisher: Springer
Journal Title: Surgery Today
Volume: 47
Issue: 2
Start Page: 166
End Page: 173
Publisher DOI: 10.1007/s00595-016-1365-x
PMID: 27324516
Abstract: Purpose: An amino acid-containing elemental diet (ED) does not require digestion for nutritional absorption, making it a good option for patients with gastrointestinal malabsorption. We conducted a randomized trial to confirm that perioperative ED enhanced the recovery of patients undergoing laparoscopic colectomy. Methods: Patients in the intervention arm received commercially available ED from the day prior to surgery until postoperative day (POD) 3, whereas patients in the control group received a conventional perioperative diet program. To verify the endpoints, "estimated minimum length of stay in hospital after surgery" (emLOS) was defined as the number of days necessary to reach all the five criteria; namely, "sufficient oral intake", "sufficient pain control", "withdrawal of intravenous alimentation", "no abnormal findings in routine examinations", and "no rise in fever". Results: A total of 102 patients were randomized, 94 of whom were analyzed (ED 45, control 49). There was no morbidity or mortality. Shorter emLOS (POD 4 vs. POD 7; p = 0.018), earlier resumption of sufficient oral intake (POD 3 vs. POD 4; p = 0.034) and faster recovery to defecation (2.2 vs. 3.1 days; p = 0.005) were observed in the ED group vs. the control group. Conclusions: The perioperative ingestion of ED by patients undergoing laparoscopic colectomy is safe and can reduce the postoperative hospital stay by supporting the acceleration of oral intake.
Rights: The final publication is available at
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 七戸 俊明

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