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室内環境中のハウスダストによる健康影響

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Title: 室内環境中のハウスダストによる健康影響
Other Titles: House dust and its adverse health effects
Authors: 荒木, 敦子1 Browse this author →KAKEN DB
アイツバマイ, ゆふ2 Browse this author →KAKEN DB
ケテマ, ラヘル メスフィン3 Browse this author
岸, 玲子4 Browse this author →KAKEN DB
Authors(alt): Araki, Atsuko1
Ait Bamai, Yu2
Ketema, Rahel Mesfin3
Kishi, Reiko4
Keywords: house dust
ハウスダスト
mite allergen
ダニアレルゲン
endotoxin
エンドトキシン
β-1,3-d-glucan
semi volatile organic compounds
準揮発性有機化合物
Issue Date: 31-May-2018
Publisher: 日本衛生学会
Journal Title: 日本衛生学雑誌
Journal Title(alt): Japanese Journal of Hygiene
Volume: 73
Issue: 2
Start Page: 130
End Page: 137
Publisher DOI: 10.1265/jjh.73.130
PMID: 29848863
Abstract: In this review, we examine house dust and its effect on inhabitants’ health. Residential house dust includes components from plants, pollens, microorganisms, insects, skin flakes, hairs and fibers. It also includes materials contaminated with chemicals from combustion, furniture, interior materials, electronics, cleaning agents, personal care products. Nowadays, most people spend their time indoors. Thus, dust is an important medium of exposure to pollutions. According to United States Environmental Protection Agency Exposure Factors Handbook, the estimated amount of dust ingestion is 30 mg/day for adults, and 60 mg/day for children over 1 year of age. Since 2003, we have been conducting epidemiological studies to find the association between the indoor environment and the inhabitants’ health. The levels of mite allergens, endotoxins, and β-1,3-d-glucan in house dust were measured as biological factors. Semi volatile organic compounds (SVOC) such as phthalates and phosphate flame retardants (PFRs) in dust were also analyzed. As a result, we found that the ORs (95%CI) of nasal and optical symptoms of sick building syndrome (SBS) were 1.45 (1.01-2.10) and 1.47 (1.14-1.88), respectively, when there was a 10-fold increase in the levels of mite allergens. There was no association of mite allergens with allergies. Endotoxins and β-1,3-d-glucan did not show any association with SBS. Regarding SVOC, increased levels of phthalates and PFR increased the risk of allergies. The association between phthalates and increased risk of allergies was clearer among children than adults. There were no gold standards of dust sampling and pretreatment methods. Thus, caution is needed when comparing findings of various studies. Methods should accurately reflect exposure levels.
Type: article (author version)
URI: http://hdl.handle.net/2115/70729
Appears in Collections:環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 荒木 敦子

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