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The clinical features of radiation cataract in patients with ocular adnexal mucosaassociated lymphoid tissue lymphoma
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| Title: | The clinical features of radiation cataract in patients with ocular adnexal mucosaassociated lymphoid tissue lymphoma |
| Authors: | Fukutsu, Kanae Browse this author | | Kase, Satoru Browse this author →KAKEN DB | | Ishijima, Kan Browse this author | | Kinoshita, Rumiko Browse this author →KAKEN DB | | Ishida, Susumu Browse this author →KAKEN DB |
| Keywords: | Ocular adnexa | | MALT lymphoma | | Female | | Bolus | | Radiation cataract |
| Issue Date: | 16-May-2018 |
| Publisher: | BioMed Central |
| Journal Title: | Radiation oncology |
| Volume: | 13 |
| Start Page: | 95 |
| Publisher DOI: | 10.1186/s13014-018-1045-7 |
| Abstract: | Background: To examine the clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma. Methods: Twenty-one patients with 26 eyes diagnosed with ocular adnexal MALT lymphoma (26 eyes), who were treated in Hokkaido University Hospital, were retrospectively reviewed based on medical records. Results: Out of the 21 patients, 16 patients (21 eyes) received radiation therapy (RT) with a total dose of 30 Gy. All cases eventually achieved complete remission. Eight of these patients (11 eyes:52.3%) required cataract surgery after RT. The mean age at surgery was 56.8 (40-70) years. The mean latency between RT and the indication for surgery was 43.3 months. The percentage of females was significantly higher in patients who required surgery (P < 0.01), compared with those without surgery. The eyes of patients who received bolus technique on radiation treatment developed cataract more frequently (P < 0.05). In contrast, none of the patients without RT required cataract surgery. Conclusions: Patients with ocular adnexal MALT lymphoma who underwent surgery for radiation cataract were seen more often in relatively young, female patients, and surgery was required about 3 years after RT. A long-term observation may be needed for patients after RT for a tumor. A female sex and the bolus technique may be risk factors for radiation cataract. |
| Rights: | http://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/71233 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 加瀬 諭
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