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pH Stability and Antioxidant Power of CycloDOPA and Its Derivatives
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| Title: | pH Stability and Antioxidant Power of CycloDOPA and Its Derivatives |
| Authors: | Nakagawa, Shiori Browse this author | | Tachrim, Zetryana Puteri Browse this author | | Kurokawa, Natsumi Browse this author | | Ohashi, Fumina Browse this author | | Sakihama, Yasuko Browse this author →KAKEN DB | | Suzuki, Takeyuki Browse this author | | Hashidoko, Yasuyuki Browse this author →KAKEN DB | | Hashimoto, Makoto Browse this author →KAKEN DB |
| Keywords: | cycloDOPA | | pH stability | | antioxidant power |
| Issue Date: | 3-Aug-2018 |
| Publisher: | MDPI |
| Journal Title: | Molecules |
| Volume: | 23 |
| Issue: | 8 |
| Start Page: | 1943 |
| Publisher DOI: | 10.3390/molecules23081943 |
| Abstract: | CycloDOPA (leukodopachrome), a well known metabolite of tyrosine, is a precursor of melanine in mammalian organisms and of the pigment betalain in plants. However, the isolation of cycloDOPA from natural sources has not been widely reported. In the present work, the stabilities of cycloDOPA and cycloDOPA methyl ester at various pH levels were studied. Both compounds were stable under acidic conditions. By contrast, both compounds were unstable when the pH was shifted from neutral to basic to form indole derivatives as major products. Based on the pH stability, cycloDOPA and its derivatives were subjected to the DPPH radical scavenging assay for the first time. |
| Rights: | © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | | http://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/71933 |
| Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 橋本 誠
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