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The data of change in macrophage gene expression which induced by perilipin 1 overexpression

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/72098
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Title: The data of change in macrophage gene expression which induced by perilipin 1 overexpression
Authors: Yamamoto, Kohei Browse this author
Miyoshi, Hideaki Browse this author →KAKEN DB
Cho, Kyu Yong Browse this author
Nakamura, Akinobu Browse this author →KAKEN DB
Greenberg, Andrew S. Browse this author
Atsumi, Tatsuya Browse this author →KAKEN DB
Keywords: perilipin1
PLIN1
Macrophage
Atherosclerosis
Issue Date: Aug-2018
Publisher: Elsevier
Journal Title: Data in Brief
Volume: 19
Start Page: 179
End Page: 182
Publisher DOI: 10.1016/j.dib.2018.05.027
Abstract: The data presented here are related to the research article entitled "Overexpression of Perilipin1 protects against atheroma progression in apolipoprotein E knockout mice". This paper describes data that were obtained from perilipin 1 (PLIN1) transgenic mice (Plin1Tg) regarding atherosclerosis. The main aim of collecting the data was to clarify the role of PLIN1 in the pathophysiology of atherosclerosis. The data were collected from C57BL/6J mice, apolipoprotein E knockout mice (ApoeKO) and Plin1Tg/ApoeKO. The atherosclerotic lesion areas of aorta were 3.3 ± 1.2% in C57BL/6J mice, 14.2 ± 3.2% in ApoeKO, and 5.6 ± 1.9% in Plin1Tg/ApoeKO. Body weight, gonadal adipose mass and plasma triglyceride concentrations were comparable among the three groups. Furthermore, PLIN1 overexpression did not affect the gene expressions related to cholesterol influx and efflux in macrophage.
Rights: http://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/72098
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 三好 秀明

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