Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
The data of change in macrophage gene expression which induced by perilipin 1 overexpression
This item is licensed under:Creative Commons Attribution 4.0 International
Files in This Item:
|
|
Related Items in HUSCAP:
|
Title: | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
Authors: | Yamamoto, Kohei Browse this author | Miyoshi, Hideaki Browse this author →KAKEN DB | Cho, Kyu Yong Browse this author | Nakamura, Akinobu Browse this author →KAKEN DB | Greenberg, Andrew S. Browse this author | Atsumi, Tatsuya Browse this author →KAKEN DB |
Keywords: | perilipin1 | PLIN1 | Macrophage | Atherosclerosis |
Issue Date: | Aug-2018 |
Publisher: | Elsevier |
Journal Title: | Data in Brief |
Volume: | 19 |
Start Page: | 179 |
End Page: | 182 |
Publisher DOI: | 10.1016/j.dib.2018.05.027 |
Abstract: | The data presented here are related to the research article entitled "Overexpression of Perilipin1 protects against atheroma progression in apolipoprotein E knockout mice". This paper describes data that were obtained from perilipin 1 (PLIN1) transgenic mice (Plin1Tg) regarding atherosclerosis. The main aim of collecting the data was to clarify the role of PLIN1 in the pathophysiology of atherosclerosis. The data were collected from C57BL/6J mice, apolipoprotein E knockout mice (ApoeKO) and Plin1Tg/ApoeKO. The atherosclerotic lesion areas of aorta were 3.3 ± 1.2% in C57BL/6J mice, 14.2 ± 3.2% in ApoeKO, and 5.6 ± 1.9% in Plin1Tg/ApoeKO. Body weight, gonadal adipose mass and plasma triglyceride concentrations were comparable among the three groups. Furthermore, PLIN1 overexpression did not affect the gene expressions related to cholesterol influx and efflux in macrophage. |
Rights: | http://creativecommons.org/licenses/by/4.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/72098 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 三好 秀明
|