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Safety of Cold Polypectomy for Colorectal Polyps in Patients on Antithrombotic Medication

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Title: Safety of Cold Polypectomy for Colorectal Polyps in Patients on Antithrombotic Medication
Other Titles: Cold polypectomy in patients on antithrombotic medication
Authors: Matsumoto, Mio Browse this author
Yoshii, Shinji Browse this author
Shigesawa, Taku Browse this author
Dazai, Masayoshi Browse this author
Onodera, Manabu Browse this author
Kato, Mototsugu Browse this author →KAKEN DB
Sakamoto, Naoya Browse this author →KAKEN DB
Keywords: Cold polypectomy
Antithrombotic medication
Post-polypectomy bleeding
Issue Date: Feb-2018
Publisher: Karger
Journal Title: Digestion
Volume: 97
Issue: 1
Start Page: 76
End Page: 81
Publisher DOI: 10.1159/000484219
PMID: 29393134
Abstract: Background: The cold polypectomy (CP) technique has been increasingly used in recent years. However, there have been few studies about post-polypectomy bleeding (PPB) in patients who underwent CP and who were on antithrombotic drugs. The objective of this study was to determine the safety of CP in patients on antithrombotic medication. Methods: The subjects were patients who underwent CP in our hospital between April 2014 and March 2016. PPB rates were examined in relation to the use of antithrombotic medication. Results: CP was performed to remove 2,466 polyps in 1,003 patients. There were 549 polyps (22.3%) in186 patients in the antithrombotic group and 1,917 polyps (77.7%) in 817 patients in the non-antithrombotic group. PPB occurred in 0.55% (3/549) of patients in the antithrombotic group and in 0.10% (2/1,917) of patients in the non-antithrombotic group, showing no significant difference (p = 0.07). Patients in the antithrombotic group in whom PPB occurred included 1 aspirin user with 1 polyp and 1 aspirin plus clopidogrel user with 2 polyps. No PPB occurred in patients on other antithrombotic agents or receiving heparin bridging. There was no significant difference between PPB rates in patients with small polyps (6-9 mm) in the antithrombotic and non-antithrombotic groups, but there was a significant difference between PPB rates in the 2 groups for patients with diminutive group (1-5 mm). Conclusion: CP is a safe procedure even in patients on antithrombotic medication.
Rights: This is the peer-reviewed but unedited manuscript version of the following article: Digestion 2018;97:76–81 (DOI: 10.1159/000484219)]. The final, published version is available at http://www.karger.com/?doi=10.1159/000484219.
Type: article (author version)
URI: http://hdl.handle.net/2115/72458
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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