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Portable negative-pressure wound therapy for pyoderma gangrenosum : Report of two cases

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Title: Portable negative-pressure wound therapy for pyoderma gangrenosum : Report of two cases
Other Titles: Portable NPWT for PG
Authors: Yamaguchi, Yasuyuki Browse this author
Yanagi, Teruki Browse this author →KAKEN DB
Sato, Kazumasa Browse this author
Yoshimoto, Norihiro Browse this author
Hirata, Yu Browse this author
Ujiie, Inkin Browse this author
Nishimura, Machiko Browse this author
Natsuga, Ken Browse this author →KAKEN DB
Shiiya, Chihiro Browse this author
Tsukinaga, Ichiro Browse this author
Shimizu, Hiroshi Browse this author →KAKEN DB
Keywords: negative-pressure wound therapy
PICO single use negative-pressure wound therapy system
portable negative-pressure wound therapy device
pyoderma gangrenosum
Issue Date: Apr-2018
Publisher: John Wiley & Sons
Journal Title: Journal of dermatology
Volume: 45
Issue: 4
Start Page: 483
End Page: 486
Publisher DOI: 10.1111/1346-8138.14180
Abstract: Pyoderma gangrenosum is a chronic non-infectious neutrophilic dermatosis that causes undermining ulcers. Topical therapies for the deep ulcers of pyoderma gangrenosum have not been established. To investigate whether negative-pressure wound therapy is effective for a pyoderma gangrenosum ulcer, we used the PICO single use negative-pressure wound therapy system (Smith & Nephew, London, UK) for two pyoderma gangrenosum patients. In these cases, the ulcers decreased in size and necrolytic tissue was removed notably. Moreover, there were no secondary infections nor was there Koebner phenomena. Our cases suggest that portable negative-pressure wound therapy can be a treatment option for deep, intractable ulcers caused by pyoderma gangrenosum. Because portable negative-pressure wound therapy devices afford increased mobility to patients, they can give the patient a better quality of life than standard negative-pressure wound therapy systems do.
Rights: This is the peer reviewed version of the following article: Yamaguchi, Y., Yanagi, T., Sato, K., Yoshimoto, N., Hirata, Y., Ujiie, I., Nishimura, M., Natsuga, K., Shiiya, C., Tsukinaga, I. and Shimizu, H. (2018), Portable negative-pressure wound therapy for pyoderma gangrenosum: Report of two cases. J Dermatol, 45: 483-486., which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 柳 輝希

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